The present study aimed to evaluate whether thymosin α1 (Tα1) increases survival rates through the improvement of immunofunction and inhibition of hepatocyte apoptosis in rats with acute liver failure (ALF). A total of 25 rats were randomly divided into the control group (CG), the model group (MG) and the treatment group (TG). The CG received an intraperitoneal injection of saline (2 ml). The A...

Massive bleeding is a serious medical complication arising from trauma, surgery, and invasive procedures. In this case, timely effective hemostasis must be applied to patients. The aim of study compare transfusion therapies guided by thromboelastogram (TEG) conventional coagulation tests (CCTs) during orthopedic focusing on blood-component function patients who underwent surgery in our hospital...

Previous studies have shown that fruits have different effects on alcohol metabolism and alcohol-induced liver injury. The present work selected three fruits and aimed at studying the effects of Syzygium samarangense, Passiflora edulis and Solanum muricatum on alcohol-induced liver injury in mice. The animals were treated daily with alcohol and fruit juices for fifteen days. Chronic treatment w...

Objective: This study evaluated the effect and clinical value of hepatic ischemic preconditioning (IP) prior to hepatectomy. Methods: 458 patients who underwent liver resection from 2001 to 2014 at Xijing Hospital were retrospectively analyzed. The patients were divided into two groups. From 2001 to 2005, the Pringle maneuver was primarily used for hepatic inflow occlusion, and 223 patients wer...

The aim of this study was to compare the organismal responses farmed and wild-caught turbot, Scophthalmus maximus, based on analyses biochemical plasma parameters, leukocyte profile, histological tissue profile gills, kidney, liver, intestine, spleen, as well gene expression stress proteins in kidney liver tissue. results revealed significant differences triglycerides (TRIG), total protein (TP)...

The herbal medicine Yin Huang Mixture (YHHJ; patent no. 200910031240.7) is an aqueous extract composed from various herbs, including Artemisia capillaries Thunb, Hypericum japonicum Thunb, Eucommia ulmoides Oliver, Rheum officinale Baill, Gardenia jasminoides Ellis, Poria cocos Wolf and Dictamnus dasycarpus Turcz. Previous studies have indicated that YHHJ treatment has a beneficial effect on am...

233 SD rats weighing 100 approximately 120 g were divided randomly into 6 groups. The animals in group I and group II received 0.1 mg/kg selenium in the form of sodium selenite only and served as the negative control and positive control, respectively. Animals in groups III, IV and V were fed with selenium as Se-enriched malt supplemented diets (0.3, 1 and 3 mg/kg), and group VI with selenium b...

BACKGROUND Paeonia lactiflora Pall. (PLP), a traditional Chinese herbal medicine, has been used for hepatic disease treatment over thousands of years. In our previous study, PLP was shown to demonstrate therapeutic effect on hepatitis with severe cholestasis. The aim of this study was to evaluate the antioxidative effect of PLP on alpha-naphthylisothiocyanate (ANIT)-induced cholestasis by activ...

AIM To evaluate the association of IFNL3 (IL28B) SNP rs4803217 with severity of disease and treatment outcome in chronic hepatitis C (CHC). METHODS The study enrolled 196 CHC Polish patients (82 women and 114 men in age 20-64) infected with hepatitis C virus (HCV) genotype 1. They were treatment naïve and qualified to pegylated interferon alpha (PEG-IFN-α) and ribavirin (RBV) therapy. The ana...

PURPOSE In our previous study, we have established the clinical significance of the SFLI (scoring formula of liver injury), the purpose of this study was to compare the SFLI system and the Child-Pugh grading system in the prediction of postoperative mortality in patients with hepatocellular carcinoma (HCC). METHODS 114 patients with HCC who underwent surgical treatment were enrolled. Accordin...