BACKGROUND Bilirubin has been seen as a toxic waste product since it is product of heme metabolism. It's the latest in a series of studies showed that the concentration of serum bilirubin is associated with various diseases such as multiple sclerosis, hypertension and cardiovascular diseases (CVD). However, no study to investigate the association between serum bilirubin and migraine, thus, our ...

Corticosteroids have been used for acute-on-chronic hepatitis B liver failure (ACHBLF) patients to inhibit overactive immunological responses. Due to the severe side effects of long-term use of corticosteroids, early identification of responders is very important for clinicians. So we conducted this study to identify efficacious indicators for response to corticosteroids. A total of 74 ACHBLF p...

BACKGROUND To evaluate the prevalence of the accessory left hepatic artery (ALHA; defined as a vessel arising from the left gastric artery, which, together with a typical left hepatic artery, supplies blood to the left lobe of the liver) and its short-term clinical implications in patients undergoing radical gastrectomy for gastric cancer. METHODS Clinical data of 1173 patients with gastric c...

UNLABELLED BACKGROUND Cichorium glandulosum Boiss. et Huet is used for treatment of liver disorders, and its effects are attributed to sesquiterpenes. This study aims to investigate the hepatoprotective effects of a sesquiterpene-rich fraction (SRF) from the aerial part of C. glandulosum on carbon tetrachloride (CCl4)-induced acute hepatotoxicity in mice, and on priming with Bacillus Calmett...

The aim of the present study was to investigate the effects of octreotide treatment on hepatic heme oxygenase-1 (HO-1) expression, together with the influence of altered hepatic HO-1 expression levels on hepatic function and fibrosis in bile duct-ligated rats. The rats were divided randomly into sham, cirrhotic, cobalt protoporphyrin and octreotide treatment groups. The expression levels of hep...

Heavy metal toxicity and bioaccumulation caused severe damage to soil, water environment as a result of industrialization/urbanization activities in developing developed countries. This has affected different trophic levels including plants, animals humans become global concern. The use various phytonutrients such Quercetin (QE) increased recent years avoid by heavy metals. Among metals, cadmiu...

Abstract Background Liver dysfunction contributes to worse clinical outcome in heart failure (HF) patients, and cholestatic enzymes are associated with mortality the setting of chronic HF (CHF). However, temporal evolutions liver function parameters stable CHF their associations outcome, have not yet been investigated. Purpose We aimed investigate detail patterns alkaline phosphatase (ALP), gam...

Hyperbilirubinemia (HB) is sometimes encountered following bile-duct cannulation in rats. It possibly originates from the reduced functioning of multidrug resistance-associated protein 2 (Mrp2) and subsequent adaptive alterations in the expression of Mrp3 and the organic anion transporting polypeptides (Oatps). Our aim was to clarify the importance of excluding bile-duct-cannulated (BDC) rats w...

COVID-19 infection usually causes respiratory distress syndrome. Liver impairment has been reported, there is no clear mechanism for liver damage. damage may be due to other factors, such as a viral or inflammations in the liver. Lack of information among residents city Najaf about differences between males and females infected with “Corona Virus” disease (“Covid-19”). In this study, we focus o...