conclusions hepatoprotective agents combined with antiviral drugs can significantly improve liver function and liver fibrosis parameters in patients with hepatitis b. results a total of 22 randomized controlled trials encompassing 1,714 cases were considered in the meta-analysis. the obtained results indicated that the combination of antiviral drug and hepatoprotective agent was better than ant...

BACKGROUND The dried roots of Scutellaria baicalensis Georgi, is known in traditional Chinese medicine as Huang Qin (H. qin), and it has been officially and traditionally used in treatment of various diseases such as hepatitis in China. Baicalein (BA), a flavonoid originally isolated from H. qin, has shown a wide range of biological activities. This study was to evaluate whether baicalein, can ...

BACKGROUND: Some research indicates that the Wistar and Sprague Dawley rats belong to closed colony strains, rather than inbred strains, which not only has some hereditary stability but also genetic polymorphism. Thus, the Wistar to SD rat liver transplantation models may not be the ideal models to study the acute rejection of rat liver transplantation. OBJECTIVE: To establish an acute rejectio...

Aim: The aim of this study was to investigate the acute effects of halothane administration on postoperative liver function tests in elective surgical patient requiring general anaesthesia at our institution. Methods: Sixty patients scheduled for elective surgeries under general anaesthesia were enrolled using convenience sampling method. The patients had no history of recent alcohol intake or ...

BACKGROUND Glutamine (Gln) supplementation is known to decrease oxidative stress and inflammatory response, enhance resistance to infectious pathogens, shorten hospital stay, and decrease medical costs of patients. This study was undertaken to evaluate the relationship between the effect of early parenteral glutamine (Gln) supplement on acute liver injury (ALI) and heat shock protein 70 (HSP-70...

Previous studies showed that C-reactive protein (CRP), an inflammatory marker, was associated with stroke severity and long-term outcome. However, the relationship between the acute-phase CRP level and discharge outcome has received little attention. We prospectively studied 301 patients with acute ischemic stroke (over a period of two weeks) from two hospital stroke wards and one rehabilitatio...

The objective of the present study was to investigate the effects of remifentanil on hemodynamics, liver function, and expression of intercellular adhesion molecule-1 (ICAM-1) in patients with liver cancer undergoing surgery. A total of 60 patients who underwent liver cancer resection in The First People's Hospital of Xiangyang, Hubei University of Medicine from January 2014 to January 2016 wer...

OBJECTIVE This experiment investigated the effects of aflatoxin B1 (AFB1) alone or mixed with ochratoxin A (OTA) and/or zearalenone (ZEA) on the metabolism, immune function, and antioxidant status of dairy goats. METHODS Fifty lactating Laoshan dairy goats were randomly assigned to one of five treatment groups (n = 10) for 14 days. Goats were fed no additive (control) or administered with 50 ...

Abstract Background Axial spondyloarthritis (axial SpA) is a chronic inflammatory disorder could lead to disability due the failure of timely treatment. The role lymphocyte-to-monocyte ratio (LMR) in axial SpA remains unclear. aim this study was investigate LMR diagnosis, disease activity classification and sacroiliitis staging. Methods Seventy-eight patients [51males 27 females; mean age 41.0 ...

Objective: Current study evaluated the utility of total antioxidant status (TAS), oxidative stress index (OSI), oxidant (TOS), ischemia-modified albumin (IMA), and ratio (IMAR) as markers in autoimmune liver disease (AILD).
 Material Methods: The included a 66 AILD patients, 22 with hepatitis (AIH), 32 primary biliary cholangitis (PBC), 12 AIH/PBC overlap syndrome, 49 healthy controls. Ser...