Two deoxyglucose (DG) derivatives, (α,β)-2-deoxy-2-amino(ethylcarbamate)-D-glucose (ECB-DG) and (α,β)-2-deoxy-2-amino(1,2-dihydroxypropyl)-D-glucose (DHP-DG), were synthesized and radiolabeled successfully with [(99m)Tc(H2O)3(CO)3](+) complex. [(99m)Tc]-ECB-DG and [(99m)Tc]-DHP-DG complexes were prepared (96% and 93% radiochemical purities respectively) by using 46 mCi of Na(99m)TcO4 in 1 mL sa...

In this work, we report the cloning and characterization of the first cell surface casein kinase II (CKII) substrate (Tc-1) of Trypanosoma cruzi, the causative agent of Chagas' disease. Analysis of the gene sequence revealed a 1,653-bp open reading frame coding for 550 amino acid residues. Northern blot analysis showed a 4.5-kb transcript that is expressed in invasive trypomastigotes but not in...

The risk of oxidative stress-related metabolic diseases increases with menopause and physical inactivity. We hypothesized that an 8-week Tai Chi (TC) training program (2 sessions in class; 2 sessions at home; 1-1:15/session) would improve antioxidant capacity and reduce cardiovascular risks in both pre- (n = 8) and postmenopausal (n = 7) sedentary women. Selected measures of physical fitness an...

BACKGROUND/AIMS Psoriasis is one of the most common inflammatory skin disorders, affecting 3% of the general population. Terminalia chebulanin (TC) is a polyphenolic compound that possesses antioxidant and anti-inflammatory activities. The current study was designed to investigate the effect of TC on psoriatic lesions. METHODS We examined the protective effect of TC against psoriatic lesions ...

To clarify biaxial fracture properties of the unidirectional carbon-fiber-reinforced plastic (CFRP) composites, a cruciform specimen with two symmetric rectangular flat dents in thickness direction was developed, and tensile tests were carried out under 0º 90º loadings. The showed three modes, namely transverse crack (TC), fiber break (FB), mixture TC FB modes (TC&FB). According to strain measu...

The compound (n-Bu4N)2Tc2Br8 was prepared by the metathesis of (n-Bu4N)2Tc2Cl8 with HBr (g) in dichloromethane and characterized by X-ray absorption fine structure spectroscopy and UV-vis spectroscopy. Analysis of the data gives a Tc-Tc distance of 2.16(1) A and a Tc-Br distance of 2.48(1) A. The Tc(III) oxidation state was inferred by the position of the edge absorption, which reveals a shift ...

Incommensurate lattice fluctuations are present in the βL phase (Tc ∼ 1.5 K) of ET2I3 (where ET is BEDT-TTF bis(ethylenedithio)tetrathiafulvalene) but are absent in the βH phase (Tc ∼ 7 K). We propose that the disorder in the conformational degrees of freedom of the terminal ethylene groups of the ET molecules, which is required to stabilise the lattice fluctuations, increases the quasiparticle...

The clinical spectrum of human disease caused by the roundworms Toxocara canis and Toxocara cati ranges from visceral and ocular larva migrans to covert toxocariasis. The parasite is not typically recovered in affected tissues, so detection of parasite-specific antibodies is usually necessary for establishing a diagnosis. The most reliable immunodiagnostic methods use the Toxocara excretory-sec...

Abstract Background Ex vivo and in detection imaging of adenosine triphosphate (ATP) is critically important for the diagnosis treatment diseases, which still remains challenges up to present. Results We herein demonstrate that ATP could be fluorescently detected imaged ex vivo. In particular, we fabricate a kind fluorescent probes, are made titanium carbide (TC) nanosheets modified with ROX-ta...

A novel gene, thyroid cancer 1 (TC-1), was found recently to be overexpressed in thyroid cancer. TC-1 shows no homology to any of the known thyroid cancer-associated genes. We have produced stable transformants of normal thyroid cells that express the TC-1 gene, and these cells show increased proliferation rates and anchorage-independent growth in soft agar. Apoptosis rates also are decreased i...