Result A range of pubertal risk factors significantly moderated the relationship between temperaments and ED severity. In particular, the relationship between TCI-Novelty Seeking and ED severity was found to be positively moderated by a negative attitude toward menstruation (p<0.01) and negatively moderated by earlier breast development (p<0.05). Similarly, the relationships between TCI-Harm Av...

OBJECTIVE To assess off-label use of the topical calcineurin inhibitors (TCIs), tacrolimus and pimecrolimus, in children during periods before and after regulatory action by the US Food and Drug Administration (FDA) in 2005. METHODS We identified new pediatric (age <20 years) users of topical tacrolimus or pimecrolimus in US Medicaid from 2001 to 2009, and examined the annual rate of drug use...

BACKGROUND Although surgery and anesthesia induce immunesuppression, remains largely unknown whether various anesthetic techniques have different immunosuppressive effects on cancer patients. Therefore, the aim of this study was to investigate the influence of total intravenous anesthesia with target-controlled infusion (TIVA-TCI) and balanced inhalation anesthesia (BAL) on the peri-operative l...

information was not included in the Methods section of our article. In contrast, however, BIS was relatively low at 3 mg ml of TCI. Although the TCI system does not predict plasma propofol concentration completely, a BIS monitor can be used during general anaesthesia. Remifentanil, however, affects the EEG characteristics during propofol anaesthesia. Therefore, we also wanted to know how remife...

Much research has been devoted to quantifying optimal or unacceptable climate conditions both generally and for specific tourism segments or activities over the last 10 years. This knowledge is not incorporated in the Tourism Climate Index (TCI), which has also been subject to other substantial critiques. To more accurately assess the climatic suitability of destinations for leisure tourism, th...

Transcutaneous immunization (TCI) is a new technique that uses the application of vaccine antigens in a solution on the skin to induce potent antibody responses without systemic or local toxicity. We have previously shown that cholera toxin (CT), a potent adjuvant for oral and nasal immunization, can induce both serum and mucosal immunoglobulin G (IgG) and IgA and protect against toxin-mediated...

BACKGROUND In the Brazilian Amazon, clinical and epidemiological frameworks of Chagas disease are very dissimilar in relation to the endemic classical areas of transmission, possibly due to genetic and biological characteristics of the circulating Trypanosoma cruzi stocks. Twenty six T. cruzi stocks from Western Amazon Region attributed to the TcI and TcIV DTUs were comparatively studied in Swi...

BACKGROUND Awake fibreoptic intubation (AFOI) is a technique used in patients with difficult airways. This study compares the suitability of remifentanil target-controlled infusion (TCI) to propofol TCI for conscious sedation during AFOI in patients with bona fide difficult airways. METHODS We recruited 24, ASA I-III patients, who were undergoing sedation for elective AFOI. Patients were rand...