Validation is a normal procedure in all fields of science once a test is developed (Hartung, 2007). The validation process is intended to provide confidence in the results, to define where the test may or may not be applied, and to give an account of test characteristics such as precision, accuracy, specificity, sensitivity, robustness, and transferability. The establishment, validation, and do...

BACKGROUND Manual validation of laboratory test results is time-consuming, creating a demand for expert systems to automate this process. We have started to set up the program "LabRespond", which covers five validation levels: administrative, technical, sample, patient, and clinical validation. We present the evaluation of a prototype of an automated patient validation system based on statistic...

The BALB/c 3T3 NRU test is probably the cytotoxicity test that has been used most frequently in formal validation programs, all of which were aimed at evaluation of cytotoxicity in predicting eye irritancy. Large-scale studies to be mentioned here are Phases I, II, and III of the Cosmetic, Toiletry, and Fragrance Association (CTFA) validation program (Gettings et al., 1991, 1992, 1994a, 1994b);...

Functional validation is one of the major bottlenecks in processor design methodology due to combined effects of increasing complexity and decreasing time-to-market. Increasing complexity of designs leads to larger set of design errors. Shorter time-tomarket requires a faster validation scheme. Simulation using functional test vectors is the most widely used form of processor validation. While ...