BACKGROUND: Tetracyclines (TCs) are broad-spectrumantibiotics that are widely used in veterinary medicine. Thepresence of TCs residues in milk is a public health concern allover the world. OBJECTIVES:This study aimed to determine TCsresiduals in pasteurized milk marketed by some dairy companiesin Tehran from April 2011 to March 2012. METHODS: 432pasteurized milk samples were purchased from supe...

background: tetracyclines (tcs) are broad-spectrumantibiotics that are widely used in veterinary medicine. thepresence of tcs residues in milk is a public health concern allover the world. objectives:this study aimed to determine tcsresiduals in pasteurized milk marketed by some dairy companiesin tehran from april 2011 to march 2012. methods: 432pasteurized milk samples were purchased from supe...

tetracyclines (tcs) are broad-spectrum antibiotics that are used widely in veterinary medicine. the present study was carried out to trace the residues of oxytetracycline (otc) and tetracycline (tc) in pasteurized milk that is marketed in tehran with the use of a high performance liquid chromatography (hplc). ninety milk samples were collected during five sequential days from the products of si...

Tetracyclines (TCs) are broad-spectrum antibiotics that are used widely in veterinary medicine. The present study was carried out to trace the residues of oxytetracycline (OTC) and tetracycline (TC) in pasteurized milk that is marketed in Tehran with the use of a High Performance Liquid Chromatography (HPLC). Ninety milk samples were collected during five sequential days from the products of si...

tetracyclines (tcs) are broad-spectrum antibiotics that are used widely in veterinary medicine. the present study was carried out to trace the residues of oxytetracycline (otc) and tetracycline (tc) in pasteurized milk that is marketed in tehran with the use of a high performance liquid chromatography (hplc). ninety milk samples were collected during five sequential days from the products of si...

By studying the literature about tetracyclines (TCs), it becomes clearly evident that TCs are very dynamic molecules. In some cases, their structure-activity-relationship (SAR) are well known, especially against bacteria, while against other targets, they are virtually unknown. In other diverse fields of research-such as neurology, oncology and virology-the utility and activity of the tetracycl...

tetracyclines are broad spectrum antibiotics which are inexpensive and widely available and have an appropriate safety profile. in addition to antibiotical effects, tetracyclines can inhibit matrix metaloproteinase and collagenase, and subsequently reduce inflammation, angiogenesis, and neovascularization. they have partial neuro-protective, anti-apoptotic and antioxidant properties. given thes...

The separation of tetracyclines (TCs) using reversed-phase liquid chromatography (LC) is proposed. The use of an amide-based stationary phase prevents the interaction of tetracyclines with the residual silanol groups and thus avoids the appearance of tailed peaks. Detection was based on using an UV spectrophotometer and gradient elution with acetonitrile-oxalic acid as mobile phase permitted go...

A technique to detect residual tetracyclines (TCs) in honey by HPLC and derivative UV-Vis spectra is examined in this study. Chromatograms of honey products often experience overlapped peaks and sloping background due to similar retention properties of components or to the presence of impurities. The derivatives provide resolution of overlapped peaks in an UV-Vis spectrum and eventually bring c...

INTRODUCTION Tetracyclines (TCs) are widely used in animal husbandry and their residues in milk may resultin harmful effects on human. The aim of this study was to investigate the presence of TCs residues in various bovine milk samples from local markets of Ardabil, Iran. METHODS One hundred and fourteen pasteurized, sterilized and raw milk samples were collected from markets of Ardabil. Tetr...