The capacity of the cell to produce, fold and degrade proteins relies on components of the proteostasis network. Multiple types of insults can impose a burden on this network, causing protein misfolding. Using thermal stress, a classic example of acute proteostatic stress, we demonstrate that ∼5-10% of the soluble cytosolic and nuclear proteome in human HEK293 cells is vulnerable to misfolding ...

Submitted for the MAR11 Meeting of The American Physical Society Glasses, Stress, Attenuation and Thermal Conductivity1 JIANSHENG WU, CLARE YU, University of California, Irvine — A wide variety of amorphous materials exhibit similar behavior in their thermal properties. Examples include universal features in the specific heat,thermal conductivity, and ultrasonic attenuation. Recent experiments ...

The thermal expansion behaviour of silicon carbide (SCS-2) fibre reinforced 6061 aluminium matrix composite subjected to the influenced thermal mechanical cycling (TMC) process were investigated. The thermal stress has important effect on the longitudinal thermal expansion coefficient of the composites. The present paper used experimental data of the thermal expansion behaviour of a SiC/Al comp...

Occupational stress is universally experienced and is emerging as a major risk factor for physical and mental illness and a key factor in poor work performance and low job satisfaction. However, the technology does not currently exist to unobtrusively measure occupational stress in real-time. Here, we describe the design and clinical validation of an automated high-definition thermal imaging sy...

This paper presents finite element analysis (FEA) of a coated and uncoated cylinder heads of a diesel engine to examine the distribution of temperature and stress. A thermal barrier coating system was applied on the combustion chamber of the cylinder heads, consists of two-layer systems: a ceramic top coat (TC), made of yttria stabilized zirconia (YSZ), ZrO2-8%Y2O3 and also a metallic bond coat...

Climatic warming is a global problem and acute thermal stressor in particular could be considered as a major stressor for wildlife. Cane toads (Rhinella marina) have expanded their range into warmer regions of Australia and they provide a suitable model species to study the sub-lethal impacts of thermal stressor on the endocrine physiology of amphibians. Presently, there is no information to sh...