1,2,3-Thiadiazole, 1,2,3-selenadiazole, and semicarbazones that are prepared from ketones promising moieties for lead compound development. New 1,2,3-thiadiazole (2c-4c) 1,2,3-selenadiazole derivatives (2d–4d) were the corresponding (2b-4b). The (2b-4b) (2a-4a). Characterization of synthesized compounds was performed using infrared spectra (IR), proton nuclear magnetic resonance (1H-NMR) spectr...

A new 1,8-naphthalimide based planar small molecular acceptor and two benzothiadiazole based wide band gap (WBG) polymer donors P1 and P2 were synthesized for nonfullerene organic photovoltaic cells (OPVs). Devices based on fluorinated polymer P2 achieved a highly improved PCE of 3.71% with an open circuit voltage (V(oc)) of 1.07 V, which is beyond the currently known levels for nonfullerene OP...

Eight novel compounds were prepared by reaction of 5-(bromo- propoxyphenyl)-10,15,20-triphenylporphyrin with oxazole thiols, 1,3,4-oxadiazole thiols and 1,3,4-thiadiazole thiols, and their structures confirmed by UV-vis, IR, 1H-NMR, MS and elemental analysis. The assessment of indirectly measured 1O(2) production rates against 5,10,15,20-tetraphenyl porphyrin (H(2)TPP) were described and the re...

Coordination compounds of Co(II), Ni(II), Cu(II), Zn(II), and Cd(II) with 1,3,4-thiadiazole-2,5-disulfonamide as ligand were synthesized and characterized by IR and UV spectroscopy, conductimetry and thermogravimetry. The parent ligand is a very weak carbonic anhydrase (CA) inhibitor, although it constituted the lead for developing important classes of diuretics. The complex derivatives behave ...

New 1,3,4-thiadiazole, 6, 7 and 1,2,4-triazole derivatives, 8, 9 containing a phenylalanine moiety have been synthesized by intramolecular cyclization of 1,4-disubstituted thiosemicarbazides, 4, 5, in acid and alkaline media, respectively; the thiosemicarbazides were obtained by reaction of hydrazide 3 with appropriate aromatic isothiocyanates. The toxicity of the synthesized compounds was eval...

Abscisic acid (ABA) is one of the plant hormones involved in the interaction between plants and pathogens. In this work, we show that tomato (Lycopersicon esculentum Mill. cv Moneymaker) mutants with reduced ABA levels (sitiens plants) are much more resistant to the necrotrophic fungus Botrytis cinerea than wild-type (WT) plants. Exogenous application of ABA restored susceptibility to B. cinere...