A foliation is of toric type when it has a combinatorial reduction singularities. We show that every on (C3, 0) without saddle-nodes invariant surface. extend the argument Cano–Cerveau for nondicritical caseto compact dicritical components exceptional divisor. These are projective surfaces and isolated branches induced to closed irreducible curves. build surface as germ along singular locus tho...

The preclinical development process of chemotherapeutic drugs is often carried out in two-dimensional monolayer cultures. However, a considerable amount of evidence demonstrates that two-dimensional cell culture does not accurately reflect the three-dimensional in vivo tumour microenvironment, specifically with regard to gene expression profiles, oxygen and nutrient gradients and pharmacokineti...