Congenital hypothyroidism is the most common neonatal metabolic disorder and results in severe neurodevelopmental impairment and infertility if untreated. Congenital hypothyroidism is usually sporadic but up to 2% of thyroid dysgenesis is familial, and congenital hypothyroidism caused by organification defects is often recessively inherited. The candidate genes associated with this genetically ...

Hashimotos encephalopathy is an autoimmune disorder, with high titres of antithyroid peroxidase antibody, usually with a clinically and biochemically normal thyroid function. Here we present a case of hashimotos encephalopathy in a 34yr old man, who presented with acute onset of cognitive impairment on a background of psychiatric illness. Initially a probability of neuroleptic malignant syndrom...

Thyroid disease is a common paediatric disorder that affects up to 3.7% of school-aged children, and it usually presents with a goitre. By far, the most frequent cause of a goitre is autoimmune thyroid disease, although a benign colloid goitre is also a common cause. The present review focuses on the diagnostic approach to a child with a hypothyroid, hyperthyroid or euthyroid goitre.

Aspergillus thyroiditis is a rare disorder detected in immunocompromised patients during disseminated infections. Early management is essential to prevent high mortality. A 61-year-old allogeneic stem cell male recipient presented with painful thyroid nodular enlargement. He had low TSH and low free T4 levels. The thyroid ultrasound showed a hypoechoic nodule; biopsy indicated suppurative Asper...

Objective: The objective of the study was to investigate lipids and thyroid profile status among women with (100 pregnant women) or without pregnancy normal) preeclampsia pre-eclamptic women). Methods: Department Obstetrics Gynecology at Pacific Institute Medical Sciences in Udaipur treated 300 patients (obstetric cases) for current case control comparative study. total lipid were examined a fa...

OBJECTIVE The study was designed to evaluate the relationship between thyroid antibodies and gland dysfunction, with the aim of finding a clinically useful threshold value of thyreoperoxidase antibodies, which could prove to be predictive for thyroid failure. MATERIAL AND METHODS The study was conducted on 99 women, ages ranging from 18-91 years (mean age: 45.5 ±17.0), were treated as outpati...

Thyroid disorders and diabetes mellitus are two of the most common endocrine conditions, which occur with greater frequency along with each other. This communication describes current knowledge about these twin diseases. Epidemiology, clinical features, laboratory abnormalities, screening and therapeutic implication of this relationship are discussed. The article underlines the clinical relevan...

Late-onset bipolar disorder is rare and can be precipitated by organic brain disorders. While the association between hyperthyroidism and mania is well described, mania or hypomania precipitated by hypothyroidism is rare. The authors present late-onset bipolar disorder in a 72-year-old woman presenting with mania and psychosis, which appear to have been precipitated by autoimmune hypothyroidism...

Thyroid storm is a life-threatening disorder that remains a therapeutic challenge. Although β-blockers are the mainstay for treatment, their use can be challenging in cases complicated by rapid atrial fibrillation and decompensated heart failure. We present a case of thyroid storm-associated atrial fibrillation and decompensated heart failure complicated by gastrointestinal dysfunction secondar...

BACKGROUND To evaluate the association between mood and anxiety disorders and thyroid autoimmunity in a community sample. METHODS A community based sample of 222 subjects was examined. Psychiatric diagnoses were formulated using the International Composite Diagnostic Interview Simplified (CIDIS), according to DSM-IV criteria. All subjects underwent a complete thyroid evaluation including phys...