Hypothyroidism is a common disorder characterized by inadequate amounts of thyroid hormones available to meet the need for thyroid at the cellular level. Typical symptoms of hypothyroidism include fatigue, weight gain/obesity, depression, cold extremities, thin/friable nails, muscle aches, headaches, decreased libido, low basal body temperature (consistently below 98.6°F), weakness, cold intole...

A girl who had a nontoxic diffuse goiter with a congenital organification defect of iodide was first seen at the age of 8 years, and since then she has been followed up for a long period. The nodularity of the thyroid gland had gradually progressed, because of intermittent failure of ingestion of thyroid hormone preparation which was followed by excess TSH secretion. 18 years later, a nodular g...

BACKGROUND Selective serotonin reuptake inhibitors (SSRIs) are typically used as antidepressants. Clinically significant SSRI-induced thyroid dysfunction is rare. CASE We report a case of hyperthyroidism induced by fluoxetine in a female patient with major depressive disorder. Her thyroid profiles indicated hyperthyroidism after a 10-week treatment with fluoxetine and were restored after disc...

Graves' disease is an autoimmune disorder, caused by thyroid-stimulating antibodies, which bind to and activate the thyrotropin receptor on thyroid cells, inducing the synthesis and release of thyroid hormones. It is a polygenic and multifactorial disease that develops as a result of complex interaction between genetic susceptibility and environmental and/or endogenous factors. Graves' disease ...

Alterations in thyroid function occur commonly in critically ill patients; however, they are rarely the primary cause of admission to the intensive care unit (ICU). In this article, the management of patients in whom abnormal thyroid function is the principal cause for ICU management is discussed. These individuals have either severe hypothyroidism or hyperthyroidism, syndromes that require ICU...

conclusions literature search revealed an increased prevalence of hypothyroidism with secondary hpth from renal failure. although there is increased prevalence of hypothyroid state in secondary hpth from renal failure, the association appears much weaker in primary hpth and again no conclusive pathological relation has been identified between the two endocrine glands. a closer look and perhaps ...

Vitiligo is an usual acquired pigmentary disorder of the skin characterized by well-circumscribed depigmented macules and patches. Though association between vitiligo thyroid disorders has been suggested, only a few studies from India overseas have paid attention to describe abnormalities, particularly in children. Hence, this study was taken up for evaluating disease childhood compared control...

Resistance to thyroid hormone (RTH), a dominantly inherited disorder usually associated with mutations in thyroid hormone receptor beta (THRB), is characterized by elevated levels of circulating thyroid hormones (including thyroxine), failure of feedback suppression of thyrotropin, and variable tissue refractoriness to thyroid hormone action. Raised energy expenditure and hyperphagia are recogn...