BACKGROUND Hürthle cell neoplasms could be benign (Hürthle cell adenoma) or malignant (Hürthle cell carcinoma). Hürthle cell carcinoma is a rare tumour, representing 5% of all differentiated thyroid carcinomas. The cytological evaluation of Hürthle cell neoplasms by fine needle aspiration biopsy (FNAB) is complicated because of the presence of Hürthle cells in both Hürthle cell adenoma and Hürt...

OBJECTIVE The current work was conducted to study the disease status and treatment results of patients with differentiated thyroid carcinoma referred for radioactive iodine therapy. METHODS Retrospective review of 78 patients with differentiated thyroid carcinoma referred for radioiodine therapy in the Nuclear Medicine Unit, King Abdulaziz Hospital and Oncology Center, Jeddah, Kingdom of Saud...

Thyroid carcinoma is the most common endocrine malignancy in the United States with increasing incidence and diagnosis but stable mortality. Differentiated thyroid cancer rarely presents with distant metastases and is associated with a low risk of morbidity and mortality. Despite this, current protocols recommend remnant ablation with radioactive iodine and evaluation for local and distant meta...

Disorders of the thyroid gland are well known in companion animals but less so in livestock. In livestock, nutritional iodine deficiencies have been of greater importance than thyroid-gland diseases, particularly in the iodine-deficient areas. Thyroid hormones have many functions in the body and, in general, regulate growth, differentiation, and the metabolism of lipids, proteins and carbohydra...

To the Editor: The diffuse sclerosing variant of papillary thyroid carcinoma (DSPTC) is a relatively rare histologic subtype of papillary thyroid carcinoma (PTC). It was first described in 1985 [1] and accounts for 2%-10% of all PTC [2-5]. The major clinical features of DSPTC include: younger age at presentation, larger tumor size, greater incidence of cervical lymph node involvement, distant m...

FDG PET in Thyroid Cancer: Thyroxine or Not? For decades, highly specific functional imaging in thyroid cancer was associated with several disadvantages of hypothyroidism. To achieve an optimal radioiodine uptake in remnant tissue and in malignant thyroid cells, it was necessary to withdraw thyroid hormone medication to increase thyroidstimulating hormone (TSH) secretion to values .30 mIU/L, if...

INTRODUCTION Sarcoidosis is an inflammatory disease characterized by non-caseating granulomas that can be present in diverse organ systems. Sarcoidosis can be associated with malignancy, presenting either preceding, during, or after chemotherapy. We herewith report a case of sarcoidosis mimicking cancer recurrence that developed after radioactive iodine therapy for papillary thyroid cancer. B...

OBJECTIVE The aim of this study is to investigate the use of (99m)Tc-methoxyisobutylisonitrile (MIBI) imaging for evaluating the treatment response of differentiated thyroid cancer (DTC) after the first administration of a high dose of (131)I. METHODS Patients with DTC who received (131)I therapy underwent (99m)Tc-MIBI imaging after successive increases in the therapeutic dose of (131)I, and ...