Total and free serum concentrations of thyroxine and triiodothyronine were measured in 122 subjects with hypothyroidism who were clinically well while receiving conventional replacement treatment with thyroxine. In a third of patients concentrations of total and free thyroxine were raised, often considerably; nevertheless concentrations of total and free triiodothyronine were usually normal. Th...

We measured serum thyroxine (free and total), triiodothyronine (free and total), thyroxine-binding globulin, and triiodothyronine uptake by talc in 97 normal men and 50 pregnant women. Mean serum thyroxine and triiodothyronine concentrations were higher in the pregnant subjects (104 vs. 78 mug/liter and 1.69 vs. 1.30 mug/liter) because of a higher mean thyroxine-binding globulin concentration (...

Objectives: The aim of the study is to determine correlation between thyroid gland elasticity with thyroxine, thyroid-stimulating hormone levels, age, gender and volume in normal population. Methods: was conducted 105 healthy cases. Thyroid evaluated axial plan using ultrasonography. Results: relationship evaluated. mean 11.95 ± 9.23 mm3. A moderate negative found kPa value observed from elasto...

BACKGROUND Thyroid hormones (THs) are well known for their genomic effects but recently several studies revealed their actions as rapid modulators of membrane receptors. In particular, fast thyroxine effect on GABA(A) receptors have been reported. We addressed question whether presynaptic mechanisms can be also involved in modulation of GABAergic transmission by thyroxine. METHODS Using patch...

Determinations of serum thyroxine concentrations were made before induction of anaesthesia, after 20 minutes and 40 minutes of anaesthesia before operation, during operation, and after the end of operation in 36 patients. After 40 minutes of anaesthesia with diethyl ether and halothane there were significantly increased endogenous serum thyroxine concentrations, but thiopentone, nitrous oxide a...

Background: Excess of dietary fats induce hyperlipidemia which causes endoplasmic reticulum (ER)stress. ER stress thyroid dysfunction and reduces serum hormone levels. Vitamin D supplementation increases levels by reducing high fat diet induced stress, inflammation autoimmunity. Objective: This study was planned to determine the effect vitamin on free total thyroxine in male albino mice. Method...

evaluation of the blood and milk biochemical parameters always is considered as effective key factor for animal health and dairy products. in order to assess the association of kappa-casein (k-cn) genetic variants with blood biochemical indicators, blood samples were randomly and individually collected from 126 iranian guilan native cattle. blood plasma was used to measure blood glucose, urea, ...

The effect of varying concentrations (0-52 mg/l) of purified thyroxine binding globulin (TBG) on the microencapsulated antibody method for free thyroxine was investigated. The results demonstrated that the free thyroxine values were strongly influenced by the concentration of thyroxine binding globulin in the samples. The standard curve could no longer be distinguished at a concentration of pur...

Thyroxine is bound to a serum protein which appears in the electrophoretogram just ahead of alpha-2 globulin (1-4). Triiodothyronine also associates with this thyroxine binding globulin (T.B.G.) but can be displaced readily with thyroxine -while triiodothyronine will not readily displace thyroxine. Deiss, Albright, and Larson (5) suggested that the firm binding of thyroxine to T.B.G. might acco...