We perform theoretical studies of stretching of 20 proteins with knots within a coarse-grained model. The knot's ends are found to jump to well defined sequential locations that are associated with sharp turns, whereas in homopolymers they diffuse around and eventually slide off. The waiting times of the jumps are increasingly stochastic as the temperature is raised. Knots typically do not retu...

The demand for noninvasive skin tightening procedures is increasing as patients seek safe and effective alternatives to aesthetic surgical procedures of the face, neck, and body. Over the past decade, radiofrequency and infrared laser devices have been popularized owing to their ability to deliver controlled heat to the dermis, stimulate neocollagenesis, and effect modest tissue tightening with...

We describe a stochastic network interdiction model for deploying radiation detectors at border checkpoints to detect smugglers of nuclear material. The model is stochastic because the smuggler’s origin-destination pair, the type of material, and the level of shielding are known only through a probability distribution when the detectors are installed. We formulate a mixed-integer program for th...

Abstract In designing a bolted joint consisting of dissimilar hollow cylinders, the load factor (the ratio an increment in axial bolt force to external tensile load) is important. However, no researches on characteristics joints members have been conducted. this paper, effects application positions, b/a outside diameter inside Young's modulus between cylinders factor, and when interface separat...

BACKGROUND The use and potential of radiofrequency energy for tissue contracture and body contouring has been established in the literature. Maximum reduction of laxity can be achieved by simultaneously tightening surface tissue and reducing unwanted fat below by the transdermal application of heat to reach and maintain tissue temperature targets within a well-defined range, inducing collagen r...

Supports for deep mine roadways located in soft surrounding rock face several problems: difficulty in applying pre-tightening force, low bearing capacity, and poor initial support. To solve these problems, this study proposes a high-pressure pre-tightening resin anchor with a compressed grouting body for use in soft and fractured rock surrounding a deep roadway. Using model experiments, we anal...

We investigate experimentally the distribution of configurations of a ring with an elementary topological constraint, a "figure-8" twist. Using a system far from thermal equilibrium, a vibrated granular chain, we show that configurations where one loop is small and the second is large are strongly preferred. Despite the highly non-equilibrium nature of the system, our results are consistent wit...

Press-fitting is a very common assembly process used in many fields, especially in the watchmaking industry. It consists of introducing a shaft in a hole (also called receptor) with a certain value of tightening (or interference). However, this process is not straightforward and it is often observed that some assemblies do not manage to hold out the time and function they are meant to. In order...