Many biological functions depend critically upon fine details of tissue molecular architecture that have resisted exploration by existing imaging techniques. This is particularly true for nervous system tissues, where information processing function depends on intricate circuit and synaptic architectures. Here, we describe a new imaging method, called array tomography, which combines and extend...

Here, the first cDNA array analysis of differential gene expression in bovine spongiform encephalopathy (BSE) is reported, using a spotted cDNA array platform representing nearly 17 000 mouse genes. Array analysis identified 296 gene candidates for differential expression in brain tissue from VM mice in late-stage infection with the 301V strain of BSE, compared with brain tissue from normal, ag...

Epilepsy, affecting about 1% of the population, comprises a group of neurological disorders characterized by the periodic occurrence of seizures, which disrupt normal brain function. Despite treatment with currently available antiepileptic drugs targeting neuronal functions, one third of patients with epilepsy are pharmacoresistant. In this condition, surgical resection of the brain area genera...

We generalize the notion of Jacobson graphs into $n$-array columns called $n$-array Jacobson graphs and determine their connectivities and diameters. Also, we will study forbidden structures of these graphs and determine when an $n$-array Jacobson graph is planar, outer planar, projective, perfect or domination perfect.

Given four complex matrices $A$‎, ‎$B$‎, ‎$C$ and $D$ where $Ainmathbb{C}^{ntimes n}$‎ ‎and $Dinmathbb{C}^{mtimes m}$ and let the matrix $left(begin{array}{cc}‎ A & B ‎ C & D‎ end{array} right)$ be a normal matrix and‎ assume that $lambda$ is a given complex number‎ ‎that is not eigenvalue of matrix $A$‎. ‎We present a method to calculate the distance norm (with respect to 2-norm) from $D$‎ to ...

in this work, some of the lattice plasmon quantum features are examined. Initially, the interaction of the far-field photonic mode and the nanoparticle plasmon mode is investigated. We probe the optical properties of the array plasmon that are dramatically affected by the array geometry. It is notable to mention that the original goal of this work is to examine the quantum feature of the array ...

BACKGROUND To identify genes associated with hepatocellular carcinoma (HCC) pathogenesis, we developed a triple combination array strategy comprising methylation, gene expression, and single nucleotide polymorphism (SNP) array analysis. METHODS Surgical specimens obtained from a 68-year-old female HCC patient were analyzed by triple combination array, and identified Dynamin 3 (DNM3) as a cand...