BACKGROUND The high prevalence of gluten sensitivity in patients with stiff-person syndrome (SPS) lead us to investigate the relationship between gluten sensitivity and GAD-antibody-associated diseases. METHODS We used ELISA assays for anti-GAD and for serological markers of gluten sensitivity. Patients were recruited from clinics based at the Royal Hallamshire hospital, Sheffield, UK. Patien...

BACKGROUND Severe respiratory syncytial virus (RSV) disease occurs predominantly in children under 6 months of age. There is no licensed RSV vaccine. Protection of young infants could be achieved by a maternal vaccine to boost titres of passively transferred protective antibodies. Data on the level and kinetics of functional RSV-specific antibody at birth and over the early infant period would ...

Refractometry is an important method for many applications in metrology, environmental monitoring, chemical and bio-medical sensing. Several types of optical fiber refractometers have been developed including those based on fiber Bragg gratings (FBGs), long period gratings (LPGs), photonics crystal fibers (PCFs), and inline interferometers [1, 2]. Yet, all these approaches require complex fabri...

To test the efficacy of passive antibody for protecting susceptible pregnant women who have been exposed to rubella high-titre human rubella immunoglobulin (HRI) was given to 20 seronegative male adult volunteers simultaneously with rubella vaccine. After receiving the intramuscular injections of HRI (750 mg of IgG) and vaccine (10(3 . 92) median tissue culture dose, Wistar RA27/3 subcutaneousl...

Le nouvel essai de Pascal Picq s’inscrit dans ces ouvrages marquants science et societe. Si le titre inspire des airs comedies, c’est surtout sous-titre, qui n’est pas annonce en couverture, “Coercition violence sexuelles chez l’Homme” reflete contenu. Sa parution fait echo a d’autres publications generalistes (e.g. Martin, 2013) particulier “L’Homme prehistorique est aussi une femme” M. Patou-...

Background: Decay of vaccine–induced antibody titres without boosting of the wild measles virus has been well documented. Revaccination against measles has reduced the prevalence of the disease worldwide. Revaccination may cause IgE induced anaphylaxis. Objective: To study measles IgG antibody in revaccinated populations and its relation to IgE induced hypersensitivity. Methods: Blood samples w...

Paired specimens of serum from patients from whom Bacteroides fragilis had been isolated were tested by complement fixation against a crude B. fragilis antigen. A high titre or a rise in titre to B. fragilis was obtained in each of five patients with infection after abdominal surgery but in none of 11 patients with postpartum pyrexia nor in nine with vaginitis.