PURPOSE Tumor redox is an important factor for cancer progression, resistance to treatments, and a poor prognosis. The aim of the present study was to define tumor redox (over-reduction) using 62Cu-diacetyl-bis(N4-methylthiosemicarbazone) (62Cu-ATSM) PET and compare its prognostic potential in head and neck cancer (HNC) with that of 2-deoxy-2-[18F]fluoro-D-glucose (18F-FDG). METHODS Thirty HN...

Objectives: To document tumoricidal events after intravenous administration of a vascular targeting agent ZD6126 in rodent liver tumors by using multiparametric magnetic resonance imaging (MRI) and F-18 fluorodeoxyglucose-micro-positron emission tomography (F-FDG micro-PET) in correlation with postmortem microangiography and histopathology. Materials and Methods: Forty rhabdomyosarcomas of 8-14...

BACKGROUND Cardiac sarcoidosis is associated with major adverse cardiac events including cardiac arrest, for which anti-inflammatory treatment is indicated. Oral corticosteroid is the mainstay among treatment options; however, adverse effects are a major concern with long-term use. It would be beneficial for providers to predict treatment response and prognosis for proper management strategy of...

BACKGROUND [18F]fluoro-2-deoxy-D-glucose ([18F]FDG) positron emission tomography (PET) is a valuable tool for monitoring response to therapy in oncology. In longitudinal studies, however, patients are not scanned in exactly the same position. Rigid and non-rigid image registration can be applied in order to reuse baseline volumes of interest (VOI) on consecutive studies of the same patient. The...

Abstract Pesticides are the necessary agrochemicals used in agricultural practice for prevention of crops from pests and diseases. may have direct effects on non-target organisms, particularly these saprobic symbiotic soilborne fungi. Dark septate endophytes (DSE) endophytic fungi that colonize living plant roots without causing a negative impact. DSE might function as mutualistic taking part n...

Introduction. This study aimed to examine the efficacy of positron emission tomography in fusion with computed (PET-CT) parameters predicting survival outcomes for patients malignant pleural mesothelioma. Material and methods. retrospectively evaluated data 250 who were followed up after a diagnosis The relationship pre-treatment [maximum standardized uptake value (SUVmax1), metabolic tumor vol...

BACKGROUND Prognostic metabolic imaging indices are needed for risk stratification for patients with locally advanced oropharyngeal cancer. METHODS We retrospectively examined pretreatment and midtreatment fluorodeoxyglucose-positron emission tomography (FDG-PET) parameters in patients with locally advanced oropharyngeal cancer who were treated with definitive chemoradiation. RESULTS A tota...

We evaluated the reproducibility and predictive value of texture parameters and existing parameters of 18F-FDG PET/CT images in Stage I non-small-cell lung cancer (NSCLC) patients treated with stereotactic body radiotherapy (SBRT). Twenty-six patients with Stage I NSCLC (T1-2N0M0) were retrospectively analyzed. All of the patients underwent an 18F-FDG PET/CT scan before treatment and were treat...