نتایج جستجو برای: tnf α

تعداد نتایج: 194893  

Journal: :journal of dental research, dental clinics, dental prospects 0
ali taghavi zenouz faculty of dentistry, tabriz university of medical sciences firoz pouralibaba zohreh babaloo masoumeh mehdipour zahra jamali

background and aims. the role of cytokines in the immunopathogenesis of oral lichen planus (olp) has received much attention. the aim of this study was to evaluate the serum levels of tnf-α and tgf-β in patients with olp in an iranian population. materials and methods. thirty-two patients with olp and 32 age-matched healthy volunteers as a control group were included in this study. serum tests ...

Journal: :مجله دانشکده پزشکی دانشگاه علوم پزشکی مشهد 0
علی علی اوصالی ali osali assistant professor, department of physical education and sport sciences, university of bonab, bonab, iranدانشگاه ملی بناب مهدی مهدی اسکندری mehdi eskandari assistant professor, department of physiology and pharmacology, school of medicine, zanjan university of medical sciences, zanjan, iranاستادیار، گروه فیزیولوژی و فارماکولوژی دانشکده پزشکی، دانشگاه علوم پزشکی زنجان، زنجان، ایران

مقدمه افزایش سن، سندروم متابولیک و عوامل التهابی از عوامل موثر در کاهش حجم مغز و افت عملکرد شناختی می باشد. هدف از این تحقیق بررسی اثرگذاری 12 هفته تمرین هوازی با شدت متوسط بر bdnf و tnf-α زنان 50-65 ساله مبتلا به سندروم متابولیک می باشد. روش کار این مطالعه به روش نیم تجربی و از نوع کاربردی با طرح پیش آزمون – پس آزمون و گروه کنترل در شهر زنجان درسال 1394 انجام شده است. 24 زن مبتلا به سندروم متا...

Journal: :iranian journal of parasitology 0
gholamreza habibi department of parasite vaccine research and production, razi vaccine and serum research institute, karaj, iran. kasra esmaeil-nia department of parasite vaccine research and production, razi vaccine and serum research institute, karaj, iran. hasan izadi department of foot and mouth disease vaccine production, razi vaccine and serum research institute, karaj, iran. orang ataie amarloie department of clinical sciences, faculty of veterinary sciences, islamic azad university, karaj, iran. asghar afshari department of parasite vaccine research and production, razi vaccine and serum research institute, karaj, iran. nadia bordbar department of quality control of biological products, razi vaccine and serum research institute, karaj, iran.

background: in this study, the pilot production of aerobic bioreactor tropical theileriosis vaccine was optimized with the aim of immunological assays for further mass production. methods: we have shown earlier the delayed type hypersensitivity (dth) assay could be used for evaluating the immunity and memory cells against specific theileria antigen in vaccinated animals. in addition, tnf-α is t...

دستمالچی, سیاوش, فرج‌زاده, داود, کریمی‌قریق, صدیقه,

Tumor necrosis factor-alpha (TNF-α) is a pro-inflammatory cytokine produced by a variety of cells, including hematopoietic and non-hematopoietic cells, malignant cells, macrophages, B lymphocytes, T lymphocytes, natural killer cells, neutrophils, astrocytes, endothelial cells, and smooth muscle cells. TNF-α is a homo-trimeric molecular whose individual subunits are composed of antiparallel beta...

Atieh Mohammadi, Fatemeh Mosaffa, Javad Behravan, Khalil Abnous Melika Ehtesham Gharaee Morteza Ghandadi, Negin Haj-Ali,

Objective(s): Acquisition of TNF-α resistance plays role in the onset and growth of malignant tumors. Previous studies have demonstrated that MCF-7 cell line and its doxorubicin resistant variant MCF-7/Adr are resistant against the cytotoxic effects of TNF-α. In this study, we investigated the role of Akt activation in resistance of MCF-7 and MCF-7/Adr against TNF-α cytotoxicity. Materials and ...

ژورنال: :فیض 0
حامد ناقوسی hamed naghoosi سیدرضا محبی sayyed reza mohebbi gastroenterology and liver diseases research center, shahid beheshti university of medical sciences, tehran, i. r. iran.تهران، ولنجک، خیابان پروانه، بیمارستان آیت ا... طالقانی، طبقه هفتم، مرکز تحقیقات بیماری های گوارش وکبد سیدمحمدابراهیم طاهائی sayyed mohamad ebrahim tahaei پدرام عظیم زاده pedram azimzadeh سارا رومانی sara romani شهره الماسی shohreh almasi مهسا خوان یغما

سابقه و هدف: فاکتور نکروزدهنده تومور آلفا (tnf-α) سایتوکاینی پیش التهابی و چند ظرفیتی است که نقش مهمی در بروز پاسخ ایمنی میزبان نسبت به ویروس هپاتیت b (hbv) ایفا می کند. هدف از این مطالعه بررسی همبستگی پلی مورفیسم تک نوکلئوتیدی جایگاه 308- پروموتر ژن tnf-α با استعداد ابتلا به عفونت مزمن هپاتیت b می باشد.مواد و روش ها: در این مطالعه مورد-شاهدی، dna ژنومیک نمونه های خون محیطی 119 فرد مبتلا به عفو...

Journal: :iranian journal of basic medical sciences 0
morteza ghandadi department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran atieh mohammadi department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran javad behravan department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran biotechnology research center, mashhad university of medical sciences, mashhad, iran khalil abnous pharmaceutical research center, department of medicinal chemistry, school of pharmacy, mashhad university of medical sciences, mashhad, iran negin haj-ali department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran

objective(s): acquisition of tnf-α resistance plays role in the onset and growth of malignant tumors. previous studies have demonstrated that mcf-7 cell line and its doxorubicin resistant variant mcf-7/adr are resistant against the cytotoxic effects of tnf-α. in this study, we investigated the role of akt activation in resistance of mcf-7 and mcf-7/adr against tnf-α cytotoxicity. materials and ...

Journal: :گوارش 0
mohammad reza fariborzi fatemeh farahmand gholam hosein fallahi mohammad taghi ashtyani masumeh hashemi azade kiumarsi

background : most diagnostic tests for biliary atresia (ba) are invasive. this study evaluates the sensitivity and specificity of serum  tumor necrosis factor-α (tnf-α) for diagnosing extra hepatic biliary duct atresia (ehba) in infants. materials and methods : infants with cholestasis who were admitted to children′s medical center hospital were evaluated. a total of 50 infants (20 with ehba an...

ژورنال: :فیزیولوژی ورزشی و فعالیت بدنی 0
ویان وثوقی بانه دانشگاه آزاد اسلامی فتاح مرادی دانشگاه آزاد اسلامی حمید آقا علی نژاد دانشگاه تربیت مدرس مقصود پیری دانشگاه آزاد اسلامی

هدف: تاثیر تمرین موازی بر وضعیت التهابی و آمادگی جسمانی دختران نوجوان غیرفعال کمتر تحت مطالعه قرار گرفته است. هدف از مطالعه حاضر بررسی تاثیر تمرین موازی به مدت چهار و هشت هفته بر شاخص­های التهابی، قدرت عضلانی و عملکرد قلبی-تنفسی در دختران نوجوان غیرفعال بود. روش شناسی: در یک مطالعه نیمه­تجربی بیست ­و سه نفر از دختران نوجوان غیرفعال بطور تصادفی به دو گروه تمرین (11=n، 28/0±07/17 سال، 7/8±45/53 ک...

Journal: :iranian journal of immunology 0
saeid abediankenari department of microbiology and immunology, mazandaran university of medical sciences, sari, iran yousef yousedzadeh department of microbiology and immunology, mazandaran university of medical sciences, sari, iran hossein azadeh department of microbiology and immunology, mazandaran university of medical sciences, sari, iran mohammad vahedi department of microbiology and immunology, mazandaran university of medical sciences, sari, iran

background: dendritic cells (dcs) are professional antigen presenting cells that have an important role in the initiation of immune response. the use of maturation factors in dendritic cell differentiation provides a promising approach in immunotherapy. objective: in this study, we compared tumor necrosis factor-α, polyribocytidylic acid, lipopolysacharide and cpg oligonucleotides in inducing d...

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