In biological membranes, alpha-tocopherols (α-toc; vitamin E) protect polyunsaturated lipids from free radicals. Although the interactions of α-toc with non-oxidized lipid bilayers have been studied, their effects on oxidized bilayers remain unknown. In this study, atomistic molecular dynamics (MD) simulations of oxidized lipid bilayers were performed with varying concentrations of α-toc. Bilay...

Recently, it has been reported that α-tocopherol (α-Toc) is effective for amelioration of liver damage. However, it is unknown whether other vitamin E analogs are effective. In this study, we investigated the effects of γ-tocopherol (γ-Toc) and tocotrienols (T3) in rats with fatty liver. Rats fed a vitamin E-deficient diet for four weeks were divided into eight groups: Control, carbon tetrachlo...

BACKGROUND KIT inhibitors, such as toceranib (TOC), and vinblastine (VBL) have not been prospectively compared in the treatment of macroscopic mast cell tumors (MCTs). Also, it is unknown whether VBL or TOC is superior for treating MCT without c-kit mutations. HYPOTHESIS/OBJECTIVES To determine the value of KIT genotyping and localization in treatment decisions for dogs with macroscopic MCT. ...

Lake sediment is an important carbon reservoir. However, little is known on the dynamics and sources of sediment organic carbon in Bosten Lake. We collected 13 surface (0–2 cm) sediment samples in Bosten Lake and analyzed total organic carbon (TOC), total nitrogen (TN), stable carbon isotopic composition in TOC (δCorg), and grain size. We found a large spatial variability in TOC content (1.8– 4...

C. Mauli Agrawal Hua Ai Eben Alsberg Luigi Ambrosio Guillermo A. Ameer Kristi Anseth Natalie Artzi Julia E. Babensee Stephen Francis Badylak Robert E. Baier Mario Barbosa Jake E. Barralet Thomas W. Bauer Rena Bizios Lars M. Bjursten Edward A. Botchwey Barbara D. Boyan John L. Brash Donald M. Brunette Jason A. Burdick Patrick T. Cahalan Mary B. Chan-Park Ashutosh Chilkoti Stuart L. Cooper Elizab...

Journal of MicroscopyVolume 284, Issue 3 p. 187-187 ISSUE INFORMATIONFree Access TOC - Information First published: 19 November 2021 https://doi.org/10.1111/jmi.12922AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text full-text accessPlease review our Terms and Conditions Use check box below share version article.I have read accept...