Previous studies suggest that carotenoids and tocopherols (vitamin E compounds) may be inversely associated with prostate cancer risk, yet little is known about how they affect prostate cancer progression and survival. We investigated whether serum A-tocopherol, B-carotene, and retinol concentrations, or the A-tocopherol and B-carotene trial supplementation, affected survival of men diagnosed w...

Determination of individual vitamin E components, such as D-αtocopherol, DL-α-tocopherol, and their esters, in food ingredients such as pre-blends, pre-mixes, and pure materials, including encapsulated and oil forms. Other compounds of accepted vitamin E activity may be measured by a method if the compounds and accuracy of measure can be ascertained. Methods should be capable of reporting α-toc...

In this study, we asked the question “does -tocopherol supplementation prevent an increase in total plasma cholesterol (TPC) concentration and reduce the deposition of cholesterol in arterial plaques of rabbits fed atherogenic diets?” Isocaloric diets containing 0.1% cholesterol to induce atherosclerosis were enriched in one of three fats: saturated fats (SAT), monounsaturated fats (MONO), or n...

Während der Herstellung, Lagerung und Wärmebehandlung unterliegt Gänseschmalz einem oxidativen Verfall. In dieser Arbeit wurde Einfluss von natürlichen synthetischen Antioxidantien Synergisten (Rosmarinextrakt, Grüntee-Extrakt, Salbeiextrakt, Alpha-Tocopherol, Tocopherol-Mischung, Propylgallat, Zitronensäure, Ascorbinsäure, Kaffeesäure, Rosmarinsäure) auf die Oxidationsstabilität untersucht. Di...

Research on new, untapped seed oil sources is receiving increased attention. In this study, 18 different samples of Tilia cordata and platyphyllos from various locations in Slovenia were collected was extracted. The compositions triglyceride fatty acids unsaponifiable compounds determined using GC-MS, while antioxidant activity evaluated the DPPH method. content seeds varied significantly, 9.1%...

Cancer development and progression are closely associated with inflammation. NF-κB (nuclear factor κB) provides a mechanistic link between inflammation and cancer, and is a major factor controlling the ability of malignant cells to resist tumour surveillance mechanisms. NF-κB might also regulate tumour angiogenesis and invasiveness and the signalling pathways that mediate its activation provide...

A comparison is made of the antioxidant activity of a water-soluble form of alpha-tocopherol complexed with bovine serum albumin (alpha-T X BSA) with that of micellar alpha-tocopherol and aqueous 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylate (Trolox) to inhibit autoxidation of linoleic acid in sodium dodecyl sulfate micelles. The peroxyl radical trapping ability of alpha-T X BSA compares f...

The lack of biochemical data to indicate the prevalence of marginal vitamin A deficiency (VAD) in the country is largely because of the difficulty of obtaining enough serum for analysis, especially from malnourished children. Efforts were therefore made to establish a high-pressure liquid chromatography system (HPLC) for the determination of retinol in micro-volumes of serum. Since our previous...

Rats were given a 200 mg/kg body weight daily dose of alpha-tocopherol by i.p. injection for 15 days. This resulted in elevated levels of glutathione in both liver and brain, and in a reduced hepatic rate of generation of reactive oxygen species. The depression of hepatic and cerebral glutathione levels in ethanol-consuming rats was prevented by simultaneous treatment with alpha-tocopherol. Oth...