We compared the ability of soluble serum transferrin receptor (TfR) concentration, quantified using the R&D Systems (Minneapolis, MN) enzyme-linked immunosorbent TfR assay, with other, more traditional indicators of iron status (total iron binding capacity [TIBC], mean corpuscular volume [MCV], percent transferrin saturation [%TS], RBC distribution width [RDW], and serum iron concentration [SIC...

This study investigated the effect of total flavone from Rhododendron simsii Planch. flower (TFR) on postischemic cardiac dysfunction and ventricular remodeling and was to test the hypothesis that TFR has an antiventricular remodeling effect through inhibition of urotensin-II receptor- (UTR-) mediated activation of RhoA-ROCK pathways. Twenty-four hours after ligation of the left anterior descen...

Bangladesh has been passing through a critical phase of fertility transition. The level of fertility started to decline since mid-seventies. The decline occurred at a rapid pace during the period 1975 to 1993/94. The total fertility rate was 6.3 in 1975 and decreased to 3.4 in 1993/94. However, since 1993/94, the level of total fertility appears to be unchanged at a level of 3.3, as observed fr...

Human development is historically associated with fertility declines. However, demographic paradigms disagree about whether that relationship should hold at very high levels of development. Using data through the late 2000s, Myrskylä, Kohler, and Billari (

We investigated here the mechanism of cytoprotection of nitric oxide (*NO) in bovine aortic endothelial cells treated with H2O2. NONOates were used as *NO donors that released *NO slowly at a well defined rate in the extracellular and intracellular milieus. H2O2-mediated intracellular dichlorofluorescein fluorescence and apoptosis were enhanced by the transferrin receptor (TfR)-mediated iron up...

North and South Korea have both experienced demographic transition and fertility and mortality declines. The fertility declines came later in North Korea. In 1990, the population was 43.4 million in South Korea and 21.4 million in North Korea and the age and sex compositions were similar. This evolution of population structure occurred despite differences in political systems and fertility dete...

BACKGROUND Efforts to develop global programs for the control of iron deficiency require simple, low-cost, and accurate indicators of iron status. OBJECTIVE We aimed to compare estimates of body iron (BI) stores, as calculated from either plasma ferritin concentration alone (BI-ferritin) or the ratio of plasma transferrin receptor (TfR) to ferritin (BI-TfR/ferritin). DESIGN Data were analyz...

Antigen preparations in the form of detergent-solubilized cell lysates could, in principle, render membrane proteins (MPs) compatible with in vitro antibody engineering technologies. To this end, detergent-solubilized cell lysates were coupled with the yeast surface display platform to affinity mature an anti-transferrin receptor (TfR) single-chain antibody (scFv). Lysates were generated from T...