Pain is a universal complaint, which needs further investigations for new pain relieving agents. Carum copticum (L.) Sprague ex Turrill is a plant in Umbelliferae family, which is mentioned to have some therapeutic effects on headache and joint pains in Iranian traditional literature, but there are not enough scientific reports to prove its effects on pain. So, we conducted to design an experim...

Thymol is a phenolic monoterpene with colorless crystalline shapes or white powder spicy, caucasian and sweet taste. Its chemical structure characterized by hydroxyl group (-OH) attached to benzene ring. It provides for the hydroxylation of P-cymine along its carvacrol’s isomer. In this molecule different therapeutic properties have been registered in molecule, such as spasmolytic, anticancer, ...

Emergence of drug-resistant strains has demanded for alternative means of combating fungal infections. Oils of Carum copticum and Thymus vulgaris have long been used in ethnomedicine for ailments of various fungal infections. Since their activity has not been reported in particular against drug-resistant fungi, this study was aimed to evaluate the effects of oils of C. copticum and T. vulgaris ...

Introduction: The aim of this study was to characterize the chemical composition and antimicrobial activity of Trachyspermum copticum essential oil (EO). Methods: The chemical composition of seed samples obtained from Mianeh city in East Azerbaijan, was assessed using gas chromatography-mass spectrometry (GC-MS). The antimicrobial activity was evaluated by disc diffusion method against methicil...

Background and Aims: Because of the toxicity and side-effects of synthetic drugs, there is a growing interest in biomedical plants. The aim of this study was to evaluate in vitro antileishmanial activity of Carum copticum essential oil against Leishmania (L) major. Materials and Methods: Nineteen experimental groups were designed to determine the effect of Carum copticum essential oil against ...