conclusions clinically, these results are logical because the required dose of alkaloids for treatment of diarrhea is lesser than the needed doses to treat addiction, arthralgia, and paralysis. results the first itm method reduced the strychnine level from 1.083 to 0.577 and brucine from 0.739 to 0.361. for the second and third itm methods, the levels of strychnine reached 0.838 and 0.812, and ...