Background: Transfusion is the mainstay treatment of patients with thalassemia major and occasionally in thalassemia intermediate. Alloimmunization is an unwanted side effect of blood transfusion. The present study intended to determine the frequency of alloimmunization in patients with β- thalassemia major and thalassemia intermediate in Southwest Iran. Patients and Methods: This was a cross-...

THE occurrence of cerebral complications following blood transfusion is rare. It is difficult to assess the part playe(d by transfusion, but a likely factor is an alteration in the coagulability of the blood. A case of cerebral thrombosis following blood transfusion is described below, followed by a short review of the post-transfusion nervous complications which have been described in the. lit...

rimum non nocere (“First, do no harm”) is an ancient reminder that patients should not be subjected to unsafe or harmful medical practices. In recent years, concern over harm to patients has gained renewed attention. Patient injury and death due to errors resulting from unsafe processes in healthcare was highlighted by the 1999 Institute of Medicine’s report “To err is human.” 1 The need to rea...

OBJECTIVE To review the pathophysiology of anemia, as well as transfusion-related complications and indications for red blood cell (RBC) transfusion, in critically ill children. Although allogeneic blood has become increasingly safer from infectious agents, mounting evidence indicates that RBC transfusions are associated with complications and unfavorable outcomes. As a result, there has been g...

BACKGROUND The need for blood transfusion in cirrhotic liver resection is difficult to determine because of inaccurate estimation of operative blood loss. Moreover, blood transfusion is detrimental to cirrhotic patients. OBJECTIVE To investigate the predictors and limitations of hepatectomy without blood transfusion for cirrhotic patients. DESIGN Retrospective study. SETTING University ho...

results a total of 6095 participants (36.4% male and 65.6% female) with the mean age of 92 (7-95) and mean ± sd of 34.6 ± 17.3 years were included in this study. fifteen persons (0.24%) were detected as hcv-positive and the highest prevalence was seen in age ≤ 12 years old (1%). a significant association was only detected between blood transfusion and hcv infection; therefore, those persons wit...

background: the differentiation between acute and latent forms of the toxoplasma gondii ( t. gondii ) infection is still considered as a complicated issue. this study was aimed to elucidate the status of infection in the blood donors and the probable importance of blood transfusion in the transmission of the infection through detecting both immunological and genetic markers of acute and latent ...