X-ray cocrystal structures of Tn5 transposase (Tnp) bound to its 19 base pair (bp) recognition end sequence (ES) reveal contacts between a beta-loop (amino acids 240-260) and positions 3, 4, 5, and 6 of the ES. Here, we show that mutations of residues in this loop affect both in vivo and in vitro transposition. Most mutations are detrimental, whereas some mutations at position 242 cause hyperac...

CONFLICT OF INTEREST NONE DECLARED The preservation of ovarian function in young patients after radical hysterectomy has an important role at the post-oncologic management and preserves life quality. Ovarian transposition is a technique in order to avoid irreversible damage to the ovaries caused by irradiation. The principal surgical ways in the transposition of the ovaries is both through lapa...

This is a serial section examination of conduction system in six hearts with tricuspid atresia. Four had regular (d-) complete transposition and two did not have transposition. The conduction system was more or less the same in all the hearts. The atrioventricular (A-V) node was in the normal position posteriorly and was short. The A-V bundle was situated in the left ventricular aspect of the s...

In two experiments, the perceptual similarity between a strong tonal melody and various transpositions was investigated using a paradigm in which listeners compared the perceptual similarity of a melody and its transposition with that of the same melody and another transposition. The paradigm has the advantage that it provides a direct judgment regarding the similarity of transposed melodies. T...

The presence of edge-disjoint Hamiltonian cycles provides an advantage when implementing algorithms that require a ring structure by allowing message traffic to be spread evenly across the network. Edge-disjoint Hamiltonian cycles also provide the edge-fault tolerant hamiltonicity of an interconnection network. In this paper, we first study the property of edge-disjoint Hamiltonian cycles in tr...

Transposable elements (TEs) are powerful motors of genome evolution yet a comprehensive assessment of recent transposition activity at the species level is lacking for most organisms. Here, using genome sequencing data for 211 Arabidopsis thaliana accessions taken from across the globe, we identify thousands of recent transposition events involving half of the 326 TE families annotated in this ...

Matrix transposition is a simple, but an important computational problem. It explores many key issues on data locality. In this paper, we will design matrix transposition algorithms on various interconnection networks for VLSI circuit design, including omega, baseline and hypercube networks. Since different interconnection networks have their own architectural characteristics and properties, an...

Two hundred forty-five patients less than 15 days of age with transposition of the great arteries with or without a ventricular septal defect or pulmonary stenosis were entered into an ongoing 20 institution treatment study between January 1, 1985 and June 1, 1986. Complete follow-up is available on all patients. The ventricular septal defect narrowed in only 1 of 36 patients with combined tran...

The piggyBac (PB) transposon is one of the most useful transposable elements, and has been successfully used for genetic manipulation in more than a dozen species. However, the efficiency of PB-mediated transposition is still insufficient for many purposes. Here, we present a strategy to enhance transposition efficiency using a fusion of transcription activator-like effector (TALE) and the PB t...

Purpose To present the results of bilateral superior rectus transposition with medial rectus recession in a case of chronic bilateral sixth nerve palsy. Observation Bilateral superior rectus transposition with medial rectus recession resulted in full correction of esotropia with resolution of horizontal diplopia, improvement in abduction, and regain of stereoacuity in our case. There was mini...