OBJECTIVE To test effectiveness of the Early Detection, Intervention, and Prevention of Psychosis Program in preventing the onset of severe psychosis and improving functioning in a national sample of at-risk youth. METHODS In a risk-based allocation study design, 337 youth (age 12-25) at risk of psychosis were assigned to treatment groups based on severity of positive symptoms. Those at clini...

Patient choice is becoming the centre of health policy in the UK and other countries. But there is ambiguity about what choice means. As the term is used in everyday life, choice is the foundation of the doctrine of patient consent. The doctor is responsible for choosing appropriate treatment, and the patient is responsible for choosing (for consenting to or refusing) what is offered and accept...

Intraoperative anaphylactic shock is an unusual complication. Different causes can be involved. Surgery of hydatid cyst is rarely responsible. About a case report of anaphylactic shock due to hydatid cyst surgery, the authors discuss the mechanisms, principles of treatment, and prevention measures of this complication.

OBJECTIVE We assessed the efficacy and clinical utility of a new occupational time-use intervention, Action Over Inertia, designed to improve occupational balance and engagement among community-dwelling people with serious mental illness. METHOD Using a randomized controlled design, we assigned 24 participants to an intervention group or standard care group. Participants were community-dwelli...

We measured the concentration of erythrocyte protoporphyrin in 43 blood samples by two fluorometric methods. In the indirect method, protoporphyrin was extracted from blood and the fluorescence of the free acid in the extract was determined with a filter-fluorometer. These results were compared with results of direct determination of protoporphyrin in the same samples. In the direct assay the f...

The slice filtration on Voevodsky’s triangulated category of motives is defined by effectivity conditions. It is constructed and studied in [HK]. An analogous filtration on the homotopy category was introduced by Voevodsky. In this note we try to get a conjectural picture of the properties of the slice filtration by systematic use of the realization functor to the derived category of Hodge stru...

Despite its high prevalence and individual as well as societal burden, migraine remains underdiagnosed and undertreated. In recent years, the options for the management of migraine patients have greatly expanded. A number of drugs belonging to various pharmacological classes and deliverable by several routes are now available both for the acute and the preventive treatments of migraine. Neverth...

Background Limited evidence suggests that Assertive Community Treatment (ACT) teams may in some cases be unnecessarily coercive. The study aimed to adapt or develop measures of client-perceived coerciveness, and of actual pressure or coercion, in an ACT setting. It also aimed to examine the association between these two constructs, as well as their associations with client sociodemographic and ...

The particle-in-cell method is generally considered a flexible and robust method to model the geodynamic problems with chemical heterogeneity. However, velocity interpolation from grid points to particle locations is often performed without considering the divergence of the velocity field, which can lead to significant particle dispersion or clustering if those particles move through regions of...