AIM To assess the extent to which a multivariate approach to modeling interrelated hematological indices provides more informative results than the traditional approach of modeling each index separately. MATERIALS & METHODS The effects of demographics and lifestyle on ten hematological indices collected from a Dutch population-based sample (n = 3278) were studied, jointly using multivariate d...

Over recent years the professional role of the radiologist has been evolved due to the increasing involvement in the clinical management of the patient. Radiologists have thus been increasingly charged by new duties and liabilities, exposing them to higher risks of legal claims made against them. Malpractice lawsuits in radiology are commonly related to inappropriate medical care or to the poor...

Incorporating an emerging therapy as a new randomisation arm in a clinical trial that is open to recruitment would be desirable to researchers, regulators and patients to ensure that the trial remains current, new treatments are evaluated as quickly as possible, and the time and cost for determining optimal therapies is minimised. It may take many years to run a clinical trial from concept to r...

Many patients lack the capacity to manage intense affects between therapy sessions, and as a result are caught in impasses as treatment becomes organized around fending off the next crisis or recovering from the last. Risk of suicide is often part of this presentation. Among the range of interventions that may help such patients emerge from impasse and treatment resistance is residential treatm...

One challenge I face in medicine is how to discuss areas of disagreement with patients. Recently, I had a gentleman come in to discuss some labs ordered by his naturopathic provider. The lab work indicated a disease process not supported by the current medical literature. Yet, he derived not only comfort from the diagnosis but also hope for treatment. He felt better on a treatment regimen that ...

Deep dentinal lesion progress is often presented as the point of no return for the specific pulp involved. In these lesions, however large variations and changes within the lesion environment may be detected. As the disease process is better studied and understood, more conservative treatments have come 5 up in the treatment of deep carious lesions. One such is a step-wise excavation procedure,...