BACKGROUND Despite recent significant therapeutic advances, vitiligo remains a clinical conundrum. Topical immunotherapy has been extensively tested in the treatment of various dermatologic disorders, especially those believed to have an immunologic basis. AIM To evaluate the role of topical diphenylcyclopropenone (DPCP) in the treatment of vitiligo. METHODS Nineteen patients with limited v...

Background: Surgical treatments of vitiligo are punch grafting, blister grafting, flip-top transplantation, split skin grafting, etc aiming at rebuilding of melanocytic population in those patients who do not respond to medical treatment . The objective of this study was determination of efficacy of blister grafting technique in the treatment of vitiligo. Methods: This study was done on 10 pati...

Vitiligo is a common inflammatory skin disease with a worldwide prevalence of 0.5% to 2.0% of the population. In the pediatric population, the exact prevalence of vitiligo is unknown, although many studies state that most cases of vitiligo are acquired early in life. The disease is disfiguring, with a major psychological impact on children and their parents. Half of vitiligo cases have a childh...

BACKGROUND Vitiligo, a common disorder of depigmentation, is often difficult to treat. Corticosteroids are known to be effective, but with modest results. Although simvastatin has been reported to be effective for immunorelated dermatologic disorders including vitiligo, controlled trials are lacking. This study was conducted to compare the efficacy of topical betamethasone valerate 0.1% cream (...

Narrow band UVB is succeeding psoralen and UVA irradiation as the main treatment of vitiligo vulgaris in several European countries. Vitamin B12 and folic acid deficiency in some vitiligo patients has prompted researchers to investigate the efficacy of these vitamins in the treatment of vitiligo. In the present controlled study we investigated the value of narrow band UVB phototherapy in the tr...

BACKGROUND Current vitiligo therapies require many months of treatment and often result in disappointing outcomes. Treatment with a 308-nm excimer laser has shown promising results in patients with vitiligo. OBJECTIVE This controlled prospective trial studied the effectiveness of the 308-nm excimer laser for treating vitiligo in Asians. METHODS Thirty-four patients (14 males and 20 females)...

We are in an era of modern medicine that is defined by rapid change. Scientists are accumulating and analyzing scores of genomic data, however, the majority of data being accumulated on vitiligo has not been appropriately archived or systemized for analysis (Alikhan et al, 2011; Spritz, 2011). The pathogenensis of vitiligo is multifactorial, and includes three main factors: genetic, immunologic...

Article history: Received on: 10/01/2017 Accepted on: 20/03/2017 Available online: 30/05/2017 Vitiligo is a skin related disease and caused by the loss of skin color in blotches. It is a worldwide problem. By the treatment of vitiligo has improve the appearance of the affected skin of a person but there is no permanent cure treatment available for this disease. Data were collected from the indi...

Although extensive research has been done to improve the treatment of vitiligo, an universal effective treatment for vitiligo is not yet available [1]. PUVA therapy has demonstrated to have immunomodulatory effects, mainly in the T lymphocyte compartment but has several adverse effects, such as skin cancer risk [2,3]. The optimization of PUVA therapy is a relevant clinical objective in the mana...