Trichloroethylene (TCE) has been identified as an environmental contaminant in groundwater. Trichloroacetic acid (TCA), dichloroacetic acid (DCA), chloral hydrate (CH), trichloroethanol (TCOH), and trichloroethanol glucuronide (TCOG) have been identified as metabolites of TCE. Studies have shown that TCA and DCA are toxicologically significant metabolites that can induce liver tumors in B6C3F1 ...

a convenient synthesis of different types of polyfunctional dihydropyrrol-2-ones via one-pot four component reactions of formaldehyde, dialkyl acetylenedicarboxylates and amines, catalyzed by trichloroacetic acid (cl3cco2h) at room temperature has been investigated. the significant advantages of this synthetic method are mild reaction conditions, available and inexpensive material, short reacti...

OBJECTIVE Trichloroacetic acid (TCAA), or trichloroethanoic acid, is a chemical analogue of acetic acid where three methyl group hydrogen atoms are replaced by chlorine. TCAAs are also abbreviated and referred to as TCAs, causing confusion with the psychiatric antidepressant drug class, especially among patients. TCAAs exist in dermatological treatments such as chemical peels or wart chemoablat...

When trichloroacetic acid (TCA) and trichloroethanol (TCE) in the urine of human subjects, rabbits, rats, and guinea-pigs were determined by Seto and Schultze's (I956) method, the recovery of TCE, added to urine, varied widely from 8i 3% in guinea-pig urine to i6-2% in rat urine. To obtain the maximum recovery of added TCE, Seto and Schultze's method was further modified to give satisfactory re...

Total urine protein was measured in 132 samples by an automated benzethonium chloride method and the Ponceau-S/trichloroacetic acid (PS/TCA) method. Of these, 27% gave a result 0.1 g/L or more higher by the benzethonium chloride method. Of this 27%, most contained an abnormally high concentration of the acute-phase reactant, alpha 1-acid glycoprotein. By assaying urine containing added alpha 1-...

The exposure of ribonuclease A to trichloroacetic acid was earlier shown to alter the conformation of the protein resulting in reduced enzymatic activity (Sagar, A. J., Subbiah, V., and Pandit, M. W. (1989) Biochim. Biophys. Acta 995, 144-150). We have studied the structure and enzymatic activity of ribonuclease A treated with trichloroacetic acid over a wide range of acid concentrations (0-40%...

Background and aim: Solar lentigines are common sun-induced benign melanocytic proliferations that present a significant cosmetic problem for many middle- aged and elderly patients. The purpose of this study was to assess the efficacy of cryotherapy in comparison to trichloroacetic acid (TCA) 33% on solar lentigines on the back of the hands (SLBH).Materials and Methods:...