Background Trichomonas vaginalis is one of the most prevalent non viral sexually transmitted diseases (STDs) in developing countries. Although several PCR based diagnostic tests are available, the performance, accuracy and sensitivity of these assays vary. Therefore, we decided to compare the performance of various diagnostic gene targets (18S rRNA, b tublin, pROS21) of T. vaginalis under simil...

Metronidazole resistance in the sexually transmitted parasite Trichomonas vaginalis is a problematic public health issue. We have identified single nucleotide polymorphisms (SNPs) in two nitroreductase genes (ntr4Tv and ntr6Tv) associated with resistance. These SNPs were associated with one of two distinct T. vaginalis populations identified by multilocus sequence typing, yet one SNP (ntr6Tv A2...

Since Trichomonas vaginalis (T. vaginalis) only manifests as a trophozoite stage during sex, it is typically transmitted sex trophozoite. The purpose of this study was to determine the concentrations copper, iron, and Eosinophil cationic protein (ECP) in vaginitis patients. Between July November 2021, 355 suspected patients who visited AL-Zahra maternity pediatrics laboratory AL-Najaf region (I...

Neutrophils are the predominant inflammatory cells found in vaginal discharges of patients infected with Trichomonas vaginalis. In this study, we examined superoxide anion (O2 (.-)) production by neutrophils activated by T. vaginalis. Human neutrophils produced superoxide anions when stimulated with either a lysate of T. vaginalis, its membrane component (MC), or excretory-secretory product (ES...

  To determine the prevalence of trichomoniasis in Sirjan city, the vaginal discharges of 500 women were examined by direct smear and culture methods from June to December 1992. ( Two hundred thirty women referred to vali-asr polyclinic and 270 to the health center number 3). The mean age of the women was 30 years and a higher percentage of referrals were between 30-34 years. In respect to the...

Albendazole (Abz) and Mebendazole (Mbz) analogues have been synthesized and in vitro tested against the protozoa Giardia lamblia, Trichomonas vaginalis and the helminths Trichinella spiralis and Caenorhabditis elegans. Results indicate that compounds 4a, 4b (Abz analogues), 12b and 20 (Mbz analogues) are as active as antiprotozoal agents as Metronidazole against G. lamblia. Compound 9 was 58 ti...

The bacterial flora associated with certain common abnormalities of the female genital tract were studied. The abnormalities included were trichomonal infestation of the vagina, the epithelial inflammation and cellular atypia associated with protozoal infestation, and erosions of the cervix. Trichomonas vaginalis infestation and marked epithelial inflammation were associated with a very varied ...

background: infection with trichomonas vaginalis is one of the most common sexually transmitted diseases (stds) in humans. the prevalence of infection in iran has been reported between 2 to 8%, depending on deferent socio-cultural conditions. this study aimed to determine the prevalence of t . vaginalis in women referred to gynecologic clinics in hamadan city, west of iran. methods: this descri...

background: trichomoniasis, caused by trichomonas vaginalis , is one of the most common sexually transmitted infections in the world. diagnosis of t. vaginalis is performed by different methods, including wet mount, culture, serological methods and pcr, which required laboratory equipments and expert laboratory personnel. the aim of this study was evaluation of immunochromatographic strip test ...

background: trichomonas vaginalis , the causative agent of trichomoniasis, is responsible for more than half of all sexually transmitted infections (stis). the present study aimed to deter­mine the frequency of t. vaginalis infection and its clinical manifestations in sympto­matic pregnant women in the area based on four different diagnostic methods. methods: a total of 162 pregnant women with ...