BACKGROUND Trauma Risk Management (TRiM) is a peer support system developed within the British Armed Forces. It aims to ensure that trauma-exposed personnel are properly supported and encouraged to seek timely help should they develop mental health problems that fail to resolve spontaneously. AIMS To summarize current knowledge about TRiM and make recommendations for further research. METHO...

The TRIM (tripartite motif) family of proteins is characterized by the presence of the tripartite motif module, composed of a RING domain, one or two B-box domains and a coiled-coil region. TRIM proteins are involved in many cellular processes and represent the largest subfamily of RING-containing putative ubiquitin E3 ligases. Whereas their role as E3 ubiquitin ligases has been presumed, and i...

BACKGROUND Cross-contamination of feed with low concentrations of antimicrobials can occur at production, transport and/or farm level. Concerns are rising about possible effects of this contaminated feed on resistance selection in the intestinal microbiota. Therefore, an experiment with pigs was set up, in which intestinal and fecal concentrations of chlortetracycline (CTC), doxycycline (DOX) a...

The influence of 1-(2-trifluoromethylphenyl)imidazole (TRIM) and 3-bromo-7-nitroindazole (3-Br-7-NI), potent and relatively selective inhibitors of neuronal nitric oxide (NO) synthase, on the antinociceptive and anticonvulsive effects of diazepam and clonazepam was investigated in mice. The effects were assessed in the writhing test and pentetrazole-induced seizures, respectively. The antinocic...

Evidence from a variety of sources indicate that allogeneic blood transfusions can induce clinically significant immunosuppression, as well as other effects, in recipients. This clinical syndrome is generally referred to in the Transfusion Medicine literature as transfusion-associated immunomodulation, or TRIM. TRIM has been linked to an improved clinical outcome in the setting of renal allogra...

Trauma risk management (TRiM) is an intensive posttraumatic stress disorder (PTSD) psychoeducational management strategy based on peer-group risk assessment developed by the UK Royal Navy (RN). TRiM seeks to modify attitudes about PTSD, stress, and help-seeking and trains military personnel to identify at-risk individuals and refer them for early intervention. This quasiexperimental study found...

The software TrIm offers implementations of tropical implicitization and tropical elimination, as developed by Tevelev and the authors. Given a polynomial map with generic coefficients, TrIm computes the tropical variety of the image. When the image is a hypersurface, the output is the Newton polytope of the defining polynomial. TrIm can thus be used to compute mixed fiber polytopes, including ...

This paper provides an introduction to one-dimensional cutting stock problems and solution procedures. The first problem considered requires that both trim loss and pattern changes be controlled. Both linear programming and sequential heuristic procedures are discussed along with the ways they can be used jointly to generate the best possible solutions to this type of problem. Two other importa...

A novel approach to fitting parabolas to scattered data is introduced by putting special emphasis on the robustness of the approach. The robust fit is achieved by not taking into account a proportion α of the “most outlying” observations, allowing the procedure to trim them off. The most outlying observations are self-determined by the data. Procrustes analysis techniques and a particular type ...