Poly(lactide-co-glycolide) (PLGA) has been widely used for scaffolding materials in tissue engineering. It degrades mainly via hydrolysis of the ester bonds into lactic acid and glycolic acid leading to the decrease in pH of the surrounding microenvironment. The current study was designed to quickly neutralize the acidic degradation products of PLGA fibrous scaffolds by incorporating tripolypho...

This paper describes the production, purification, and immobilization of l-asparaginase II (ASNase II) in chitosan nanoparticles (CSNPs). ASNase II is an effective antineoplastic agent, used in the acute lymphoblastic leukemia chemotherapy. Cloned ASNase II gene (ansB) in pAED4 plasmid was transformed into Escherichia coli BL21pLysS (DE3) competent cells and expressed under optimal conditions. ...

Macroor micro-porous chitosan membranes have been utilized as adsorptive membrane for the removal of metal ions, organic macromolecules or bioseparation of protein mixtures. The removal or separation mechanism is not based on physical size retention but based on the high adsorption capability of chitosan to the target solutes. For this purpose, it is important that large macro or micro pores an...

Bioactive composites that enable the formation of calcium phosphates have received increased attention over the last decade, in the development of osteoconductive biomaterials for orthopaedic applications. In this work, tripolyphosphate (TPP)-cross-linked chitosan/gelatin composites (TPP-CG) were prepared for the growth of shape- and size-controlled calcium phosphates on/in the composites. The ...

Adsorption and precipitation reactions often dictate the availability of phosphorus in soil environments. Tripolyphosphate (TPP) is considered a form of slow release P fertilizer in P limited soils, however, investigations of the chemical fate of TPP in soils are limited. It has been proposed that TPP rapidly hydrolyzes in the soil solution before adsorbing or precipitating with soil surfaces, ...

HDB disease is caused by Xanthomonas oryzae pv.oryzae, an important in rice plants. Recently, many organic compounds based antibacterial agents like chitosan are being developed. The potential raw materials for producing Black Soldier Fly (BSF) exuviae. At the development, was formulated with other ingredients such as kipahit leaves (Tithonia diversifolia) extract. This study aimed to synthesiz...