Bestrophin-1 (Best-1) is an integral membrane protein, defects in which cause Best vitelliform macular dystrophy. Best-1 is proposed to function as a Cl- channel and/or a regulator of Ca++ channels. A tetrameric (or pentameric) stoichiometry has been reported for recombinant best-1. Using a combination of gel exclusion chromatography and velocity sedimentation we examined the quaternary structu...

When concentrated dispersions of tripalmitin in Triton X-100 are added to reaction mixtures containing soluble beef liver lipase, the rate of hydrolysis of tripalmitin increases with incubation time. When the diluted substrate is aged at 37 degrees C for 3 hr before the addition of enzyme, the rate of hydrolysis is greater than the rate with freshly diluted dispersions and is constant for at le...

This study determined the effect of surfactant Triton X-100 (1%) on biodegradation of various by polycyclic aromatic hydrocarbons (PAHs) by Pseudomonas sp. PSS6. Sprayed-plate experiments were performed to find the degrading capability of the test isolate. The test strain efficiently degraded PAHs to a greater extent compared to other isolates forming an intensive clear zone in Bushnell–Haas ag...