OBJECTIVES To investigate whether the human sciatic nerve might have a consistent somatotopic organization according to proximal fascicle input by spinal nerves. METHODS Twelve patients (55.3 ± 15.5 years) with confirmed lesions of either the L5 or S1 spinal nerve root underwent magnetic resonance neurography of sciatic nerve fascicles including thigh and knee levels (T2-weighted sequence wit...

OBJECTIVES The efficacy of combined lumbar plexus-sciatic nerve blocks was compared to epidural anesthesia in patients undergoing total knee surgery. PATIENTS AND METHODS The study included 80 American Society of Anesthesiologists (ASA) Physical Status I-III patients (age range 18 to 65) undergoing knee surgery. The patients were randomly divided into one of two groups. Epidural anesthesia wa...

BACKGROUND Diabetes is associated with micro- and macro-vascular complications affecting several organs. Oxidative stress plays a crucial role in the etiology of vascular disease in diabetes. OBJECTIVES The present study aimed to investigate the beneficial effect of troxerutin on diabetes-induced histopathological damages in rat aorta with focusing on its antioxidative actions. MATERIALS AN...

UNLABELLED Total knee replacement (TKR) produces severe postoperative pain. Peripheral nerve blocks can be used as analgesic adjuncts for TKR, but the efficacy of femoral nerve blocks alone is controversial. The sciatic nerve innervates posterior regions of the knee; thus, performance of both sciatic and femoral nerve blocks may be necessary to improve analgesia after TKR. We performed this stu...

background: brain hypoxia-ischemia is a human neonatal injury that is considered a candidate for stem cell therapy. methods: the possible therapeutic potential of human umbilical cord blood (hucb) stem cells was evaluated in 14-day-old rats subjected to the right common carotid occlusion, a model of neonatal brain hypoxia-ischemia. seven days after hypoxia-ischemia, rats received either saline ...

Background and Aim: Sciatic nerve injury is a common condition that can lead to significant functional deficits. Although current treatments are effective in reducing symptoms, more safer still required. In this research, the effect of trans-anethole (TA) was investigated on improving sciatic function rat model. Methods Materials/Patients: Twenty-eight adult male Wistar rats were divided into f...

Injury severity, operative technique and nerve regeneration are important factors to consider when constructing a model of peripheral nerve injury. Here, we present a novel peripheral nerve injury model and compare it with the complete sciatic nerve transection method. In the experimental group, under a microscope, a 3-mm longitudinal incision was made in the epineurium of the sciatic nerve to ...

Introduction: Prior qualitative and quantitative studies have reported morphological changes that occur in nerve fibers and non-neuronal cells of peripheral nerve during the lifetime of the rats. Previous studies suggest that Aloe Vera has some beneficial and therapeutic effects such as anti-oxidant effects. In the current study, we have evaluated histological and histomorphometric changes of Sc...

Dorsal and ventral divisions of ventral rami of lower lumbar and sacral spinal nerve were found to pass ventral and dorsal to the piriformis muscle respectively. These divisions joined each other below the piriformis muscle to form sciatic nerve. This low formation of sciatic nerve was observed in distal part of left gluteal region of a 50-year-old male cadaver. The sciatic nerve thus formed pa...

Advancements in hip arthroscopy are astounding. Circumferential labral reconstruction, augmentation, and capsular reconstruction valuable tools. Beyond the “comfort zone” of intra-articular realm, new frontiers include peritrochanteric space, a similarity to subacromial space shoulder makes transition attainable. In contrast, subgluteal is seen as outside box. Sciatic nerve entrapment (SNE), is...