In a 5-year period, 254 patients with community-acquired pneumonia were attended to. Transtracheal aspiration (TTA) could be performed on 119 patients, blood cultures were performed on 201 patients, and 74 patients underwent serologic examinations. By use of these procedures, an etiologic diagnosis was established in 93 cases. Streptococcus pneumoniae was the most common pathogen as it was foun...

Following amputation, people with transfemoral amputation (TFA) and transtibial amputation (TTA) adapt with asymmetrical movements in the spinal and lower-limb joints. The aim of this review is to describe the trunk, lumbopelvic, and hip joint movement asymmetries of the amputated limb of people with TFA and TTA during functional tasks as compared with the intact leg and/or referent leg of nond...

L-carnitine is important for the catabolism of long-chain fatty acids in the mitochondria. We investigated how the triacylglycerol (TAG)-lowering drug 2-(tridec-12-yn-1-ylthio)acetic acid (1-triple TTA) influenced lipid metabolism in carnitine-depleted, 3-(2,2,2-trimethylhydrazinium)propionate dehydrate (Mildronate; meldonium)-treated male Wistar rats. As indicated, carnitine biosynthesis was i...

BACKGROUND Soluble stem cell factor (SCF) has been shown to mobilize bone marrow stem cells and improve cardiac repair after myocardial infarction (MI). However, the effect of membrane-associated SCF on cardiac remodeling after MI is not known. The present study investigated the effects of cardiomyocyte-specific overexpression of the membrane-associated isoform of human SCF (hSCF) on cardiac fu...

Adaptive epigenetic changes and toxicity often accompany constitutive expression of a transgene or knockout of an endogenous gene in mice. These considerations potentially limit the usefulness of transgenic technology in studying the in vivo functions of a gene. Using conditional gene expression technology, it is possible to override such restrictions to achieve temporal and tissue-specific man...

Ninety-six sputum specimens from patiens with pneumonia were microscopically screened for leukocytes and buccal squamous epithelial (BSE) cells. Cultures of these specimens were compared with cultures of paired transtracheal aspirates (TTA). Agreement between sputa with less than 25 BSE cells per 100X field and TTA was good (79%). Only 27% of the specimens with greater than 25 BSE cells per 100...

Background The 4-thia fatty acid tetradecylthiopropionic acid (TTP) is known to inhibit mitochondrial β-oxidation, and can be used as chemically induced hepatic steatosis-model in rodents, while 3-thia fatty acid tetradecylthioacetic acid (TTA) stimulates fatty acid oxidation through activation of peroxisome proliferator activated receptor alpha (PPARα). We wished to determine how these two com...

Thermo-mechanical reliability is one major issue in solid-state lighting. Mismatches the coefficients of thermal expansion (CTE) between high-power LED packages and substrates paired with temperature changes induce mechanical stress. This leads to a degradation modules by crack formation solder interconnect and/or delamination substrate, which turn increases junction thus decreases light output...

White light-emitting diodes (WLEDs) revolutionized the lighting industry providing high energy efficiency and a long lifetime. The recent development of efficient ultraviolet (UV) LEDs pushed forward WLEDs based on mixtures down-shifting phosphors current challenges are focused design sustainable light converting materials with tunable correlated color temperature (CCT) rendering index (CRI). H...

The gadolinium(III) chelates Gd(dtpaH2), Gd(hfac)3, Gd(tta)3 and Gd(qu)3 with dtpa1⁄4 1,1,4,7,7-diethylenetriaminepentaacetate, hfac1⁄4 hexafluoroacetylacetonate, tta1⁄4 thenoyltrifluoroacetonate and qu1⁄4 8-quinolinolate (or oxinate) show a phosphorescence under ambient conditions. While the UV emission of Gd(dtpaH2) at kmax 1⁄4 312 nm comes from a metal-centered ff state, the bluish (kmax 1⁄4...