background: both azadirachtin and rotenone, two botanical pesticides have shown inhibit the growth of cultured insect cells. the inhibitory effect of rotenone on cell growth is through disruption of electron transport chain, but exact mechanism of effect of azadirachtin on growth of cell is unknown. this study was carried out to compare the effect of these phytochemical on oxygen consumption by...

Tubo-ovarian abscess in pregnancy is extremely rare. In this report, we present a patient who had asymptomatic tubo-ovarian abscess during pregnancy. It was diagnosed incidentally immediately after vaginal delivery. Emergency laparotomy was followed and surgical findings included a 4 cm-sized, right, ruptured tubo-ovarian abscess with massive purulent contamination of the whole pelvic cavity. R...

background: most cancer cells become resistant to anti-cancer agents. in the last few years, a new approach for targeted therapy of human cancer has been developed using immunotoxins which comprise both the cell targeting and the cell killing moieties. methods: in the present study, the recombinant shiga toxin a1 subunit fused to human granulocyte-macrophage colony stimulating factor (a1-gm-csf...

in this syudy a continuous bovine kidney cell line derived from a primary bovine kidney cells was established for the first time in iran. the cells were originating from two-day-old normal male calf of holstein breed. the cell cultures were continuously passaged following complete proliferation of primary cells. the specific properties or characteristics of the cell were defined using cytogene...

Defining determinants of T cell fate is central to understanding adaptive immunity and the design of effective vaccines. Tubo et al. demonstrate that intrinsic properties of T cell receptor signaling dictate whether CD4 T cells adopt predominantly type 1 helper or follicular helper T cell phenotypes in response to bacterial or viral infection.

By studying BALB/c mice deficient in immune components, we show that the protective immunity to rat ErbB2(+) tumors rests on the Ab response elicited by the electroporation of a DNA vaccine encoding the extracellular and transmembrane domains of rat ErbB2. In vivo, the adoptive transfer of vaccine-elicited anti-rat ErbB2 Abs protected against a challenge of rat ErbB2(+) carcinoma cells (TUBO ce...

background: the rh antigens are expressed as parts of a protein complex in the rbc membrane. this complex is a tetramer, consisting of two molecules of rhag and two molecules of rh proteins. to express rhd in rbc membrane, expression of rhag is essential. this co-expression only occurs in the erythroid lineage. k562 cell line has an erythroid lineage. materials and methods: cord blood was used ...

Tubo-ovarian abscess is a rare but potentially serious event that can occur after uterine artery embolization (UAE). We describe herein two cases of severe inflammatory tubo-ovarian abscesses. Two women presented with severe abdominal pain, cramping, and fever several months after UAE. Abdominal computed tomography demonstrated an enlarged tubo-ovarian mass, suggestive of an abscess. Percutaneo...

one of the major complications in cancer chemotherapy is the development of resistance, and cisplatin, as one of the important medicines in treatment regimens of different cancers is not excluded. one of the most described cellular defense mechanisms involved in resistance is glutathione (gsh) and in this study, the effects of cisplatin on the total intracellular gsh level (gshi) in some sensit...

Introduction: A tubo-ovarian abscess reflects an inflammatory adhesion of pelvic organs including the fallopian tube and ovary forming a palpable complex, which represents the ultimate process of pelvic inflammatory disease (PID). Fistula formation between the sigmoid colon and other pelvic organs such as the bladder, uterus, and ovary is mainly caused by colorectal cancer or diverticulitis. Ho...