The biological mechanisms leading to periprosthetic osteolysis involve both chemokines and the monocyte/macrophage cell lineage. Whether MCP-1 plays a major role in macrophage recruitment in the presence of wear particles is unknown. We tested two hypotheses: (1) that exogenous local delivery of MCP-1 induces systematic macrophage recruitment and (2) that blockade of the MCP-1 ligand-receptor a...

In this investigation the friction and wear performance of GUR 1020 medical grade ultra-high molecular weight polyethylene (UHMWPE) polymer under dry sliding, distilled water and egg albumen lubrication conditions were evaluated. The sliding experiments were carried out on a pin-on-disc tribometer. The contact configuration used was a polymer pin on a rotating AISI 304L stainless steel disc. We...

BACKGROUND At present time the number of implantations of joint replacements as well as their revisions increases. Higher demands are required on the quality and longevity of implants. The aim of this work was to determine the degree of oxidative degradation and the amount of free/residual radicals in selected ultra-high molecular weight polyethylene (UHMWPE) components of the joint replacement...

The objective of this study was to assess the suitability of using multidirectional pin-on-disk (POD) testing to characterize wear behavior of retrieved ultrahigh molecular weight polyethylene (UHMWPE). The POD wear behavior of 25 UHMWPE components, retrieved after 10 years in vivo, was compared with 25 that were shelf aged for 10-15 years in their original packaging. Components were gamma ster...

The data included here provides a basis for understanding "Interior morphology of high-performance polyethylene fibers revealed by modulus mapping" (K.E. Strawhecker, E.J. Sandoz-Rosado, T.A. Stockdale, E.D. Laird, 2016) [1], in specific: the multi-frequency (AMFM) atomic force microscopy technique and its application to ultra-high-molecular-weight Polyethylene (UHMWPE) fibers. Furthermore, the...

Delamination is a common failure mechanism in ultra-high molecular weight polyethylene (UHMWPE) tibial inserts [Wright and Rimmnac, 1988]. Changes in polyethylene mechanical properties, such as subsurface embrittlement due to oxidation, may promote crack propagation. The assessment of through-thickness properties may, therefore, provide insight into delamination mechanisms. Using the small punc...

A composite hip prosthesis (CHP) made from alumina reinforced ultra high molecular weight polyethylene (UHMWPE) was designed and manufactured. The main objective of the study was to fabricate the composite hip prosthesis which would be an ideal replacement of metallic one as bone is a composite material consisting of collagen fibre matrix and embedded hydroxyapatite mineral. With this idea we d...

Abbreviations MEMS Microelectromechanical systems NEMS Nano-electromechanical systems PCL Polycaprolactone PET Polyethylene terephthalate PGA Polyglycolic acid PLA Polylactic acid PU Polyurethane PTFE Poly(tetrafl uoroethylene) PMMA Polymethylmethacrylate UHMWPE Ultrahigh molecular weight polyethylene

El polietileno de ultra alto peso molecular (UHMWPE por sus siglas en inglés) ha sido el estándar oro para los reemplazos rodilla durante más cinco décadas. Este biomaterial, utilizado ampliamente sector ortopédico, constantemente modificado disminuir su tasa desgaste las prótesis rodilla. Hoy día, totales tienen una supervivencia del 95 % después 10 años, 88.7 15, y 82 25 años. Sin embargo, la...

UHMWPE has exhibited excellent performance when used as contact surfaces in tribological contacts. Traditionally, only grades, with narrow particle size and molecular weight distribution, have been deemed suitable for such applications. Now, various grades are available that different from each other based on their distribution. The question of whether the affects its properties presents a rese...