Ultra high molecular weight polyethylene (UHMWPE) submicron wear debris particles in total joint replacement (TJR) prosthesis have been observed clinically to cause osteolysis. In this study, the formation of UHMWPE submicron wear debris was investigated by modeling a nanoscale asperity on the surface of a CoCr femoral component of a total knee replacement (TKR) prosthesis using a Si3N4 AFM com...

Introduction: Ultra high molecular weight polyethylene (UHMWPE) is a common bearing component in Total Knee Replacement (TKR) implants, and its susceptibility to wear continues to be the long-term limiting factor in the life of these implants. Novel material modifications have been introduced to reduce UHMWPE wear rates and thus improve the life of TKRs. Radiation and crosslinking of UHMWPE hav...

BACKGROUND Periprosthetic osteolysis is a major cause of aseptic loosening in joint arthroplasty. This study investigates the impact of CT (calcitonin) deficiency and CT substitution under in-vivo circumstances on particle-induced osteolysis in Calca -/- mice. METHODS We used the murine calvarial osteolysis model based on ultra-high molecular weight polyethylene (UHMWPE) particles in 10 C57BL...

Cold atmospheric plasma (CAP) treatment was used on ultra-high molecular weight polyethylene (UHMWPE), a common articulating counter material employed in hip and knee replacements. UHMWPE is a biocompatible polymer with low friction coefficient, yet does not have robust wear characteristics. CAP effectively cross-links the polymer chains of the UHMWPE improving wear performance (Perni et al., A...

INTRODUCTION: Vitamin E-stabilized, radiation cross-linked ultra-high molecular weight polyethylene (UHMWPE) is used in total joint arthroplasty as a bearing surface with low wear and improved mechanical properties compared to irradiated and melted UHMWPE [1]. Vitamin E stabilizes the residual free radicals trapped in the material after irradiation and ensures oxidative resistance, thus resulti...

Ultra-high-molecular-weight polyethylene (UHMWPE) has been applied in orthopedics, as the materials of joint prosthesis, artificial ligaments, and sutures due to its advantages such as high tensile strength, good wear resistance, and chemical stability. However, postoperative osteolysis induced by UHMWPE wear particles and poor bone-implant healing interface due to scarcity of osseointegration ...

In the present work, novel Ultra-high molecular weight polyethylene (UHMWPE) composites reinforced with 3wt. %, 6wt. %, 9wt. %, 12wt. % and 15wt. % PEEK particles are fabricated by using hot compression moulding technique and mechanical properties are investigated. Experiments were conducted as per ASTM standards to evaluate the properties of tensile, flexural, impact, and microhardness. The re...

Wear debris-induced osteolysis remains the greatest limitation of long-term success for total joint replacements with ultra-high molecular weight polyethylene (UHMWPE) bearings. To address oxidative degradation post-gamma irradiation, manufacturers are investigating the incorporation of antioxidants into PE resins. Similarly, larger molecular weight monomers have been developed to increase cros...

Recently, some novel surface engineering techniques have been developed, which may be used for extending lifetime of artificial joints; however, the full potential will not be realised until the tribological behaviour of surface engineered bio-medical materials has been fully characterised. In the present investigation, a pin-on-disc tribometer has been used to evaluate the tribological respons...

Ultra-high molecular weight polyethylene (UHMWPE) thin film was coated onto Ti6Al4V alloy specimens using dip coating method. Tribological performance of this coating (thickness of 19.6 ± 2.0 μm) was evaluated using 4 mm diameter Si(3)N(4) ball counterface in a ball-on-disk tribometer. Tests were carried out for different normal loads (0.5, 1.0, 2.0 and 4.0 N) and rotational speeds of the disk ...