PURPOSES To explorer the serum level of pro- and anti-inflammatory cytokines in the patients of ulcerative colitis and irritable bowel disease. And analyze the correlation between the cytokine's levels and disease's activity of ulcerative colitis patients. METHODS Serum cytokines of ulcerative colitis and irritable bowel syndrome with diarrhea patients including IL-6, IL-10, IL-13, IL-17, TNF...

a 45-year-old female patient with a diagnosis of ulcerative colitis complicated with composite lymphoma in the spleen and para-aortic lymph node presented with a one-month history of malaise, weakness and fatigue. only mesalamine kept ulcerative colitis under control. in physical examination, splenomegaly was revealed and pancytopenia was obtained from laboratory data. computed tomography scan ...

ulcerative colitis and crohn's disease are chronic, relapsing, inflammatory conditions defined by their phenotypic features. family studies have identified a clear genetic influence on disease susceptibility and expression. molecular studies have identified specific genes that predispose individuals to the development of inflammatory bowel disease. some of these genes are specific to either ulc...

Conventional medical treatment for ulcerative colitis can have limited efficacy or severe adverse reactions requiring additional treatment or colectomy. Hence, different biological agents that target specific immunological pathways are be-ing investigated for treating ulcerative colitis. Anti-tumor necrosis factor (TNF) agents were the first biologics to be used for treating inflammatory bowel ...

Release Date: December 14, 2007; Valid for credit through December 14, 2008 Target Audience This activity is intended for physicians specializing in the fields of gastroenterology and internal medicine, as well as other healthcare professionals conducting research and/or providing care for individuals with ulcerative colitis. Goal The goal of this activity is to define the latest issues challen...

The exact relationship between ulcerative colitis and auto-immune haemolytic anaemia in these two cases is not known and it is possible that it is fortuitous. However, since there is evidence that both diseases have an immunological basis, it would seem likely that the cause of the two conditions is in some way linked. In any event, it is important to consider haemolysis as a cause of anaemia i...

The incidence of lactose malabsorption was investigated in 85 patients with ulcerative colitis and 71 patients with Crohn's disease by means of lactose tolerance tests and disaccharidase determinations in small intestinal mucosa. Eight patients with ulcerative colitis (9%) and four with Crohn's disease (6%) had lactose malabsorption. A control group displayed a similar incidence. It is conclude...

Luminal concentrations of short chain fatty acids (SCFA), ammonia, sodium and potassium were measured in colonic dialysate of 16 control subjects and in 65 cases with ulcerative colitis (UC), which were graded according to mucosal changes into mild (1), moderate (2), or severe (3) inflammatory activity. Sodium concentrations were mildly but not significantly increased in severe ulcerative colit...

The inverse correlation of appendectomy and ulcerative colitis is well known, but the effect of appendectomy on the clinical course of ulcerative colitis remains unclear. Although the majority of opinions were negative for the therapeutic advantage of appendectomy in patients with ulcerative colitis, advocates for positive effect of appendectomy have been proposed in a few case reports and a pr...

aim : the present study evaluated the association between g241r and k469e polymorphisms of intercellular adhesion molecule 1 gene and inflammatory bowel disease in iranian population.   background : inflammatory bowel disease including ulcerative colitis and crohn’s disease, is a chronic idiopathic inflammatory disease of the gastrointestinal tract. there are two single base polymorphisms of in...