Urethane is a fermentation by-product and a potent animal carcinogen. Human exposure to urethane occurs through consumption of alcoholic beverages and fermented foods. Recently, CYP2E1 was identified as the primary enzyme responsible for the metabolism of C-carbonyl-labeled urethane. Subsequently, attenuation of urethaneinduced cell proliferation and genotoxicity in CYP2E1-/mice was reported. P...

A method has been developed to investigate the extent of polymer cross-linking that results following in situ photopolymerization of an acrylate-functionalized phospholipid assembly adsorbed onto a stabilized, membrane-mimetic film produced from a polyelectrolyte multilayer (PEM) on polytetrafluoroethylene (PTFE) grafts. The acrylate phospholipid monomer was synthesized, prepared as a unilamell...

In this study, the mechanism of self-initiation in spontaneous thermal polymerization of ethyl and n-butyl acrylate is explored using first-principles calculations. Density functional theory (with B3LYP functional and 6-31G* basis set) was used to study [4 + 2] and [2 + 2] cycloaddition reactions on the singlet and triplet potential energy surfaces. Diels-Alder (DA) dimers of ethyl acrylate [6-...

Anesthetics are often used to characterize the activity of single neurons in vivo for their advantages such as reduction of noise level and convenience in noxious stimulations. Urethane has been a widely used anesthetic in thalamic studies under the assumption that sensory signals are still relayed to the thalamus under urethane anesthesia and that thalamic response would therefore reflect the ...

A novel acrylate monomer containing 4H-pyran-4-one and 1,2,3-triazole ring, {1-[4-(4-oxo-6-phenyl-4H-pyran-2-yl)benzyl]-1,2,3-triazol-4-yl}methyl acrylate was synthesized by the reaction of 2-{4-[(4-(hydroxymethyl)-1,2,3-triazol-1-yl)methyl]phenyl}-6-phenyl-4H-pyran-4-one with acryloyl chloride in the presence of triethylamine. The structure of the acrylate monomer was established on the basis ...

We describe the synthesis of bromo-tert-butyloxycarbonyl (Br-t-BOC)-amino-protected monomers 2-((1-bromo-2-methylpropan-2-yl)oxycarbonylamino)ethyl (meth)acrylate 3a,b. For this purpose, 2-isocyanatoethyl (meth)acrylate 1a,b was reacted with 1-bromo-2-methylpropan-2-ol (2a). The free radical polymerization of (Br-t-BOC)-aminoethyl (meth)acrylates 3a,b yielded poly((Br-t-BOC)-aminoethyl (meth)ac...

Acrylate grouting material has been widely used in dams, tunnels and other underground buildings. This paper introduces the basic components of acrylate grouting material, then the reaction mechanism and dynamics of gelation process are discussed based on the theory of free radical polymerization. By measuring the relationship between gelation time and the concentration of initiator ammonium pe...

The title compound, C(17)H(15)NO(5), adopts an E conformation with respect to the C=C double bond of the phenyl-acrylate unit. The phenyl ring and methyl acrylate group of the phenyl-acrylate unit are disordered over two sets of sites with site-occupancy ratios of 0.705 (5):0.295 (5) and 0.683 (3):0.317 (3), respectively. The mean plane through the benzene ring of the phenyl acrylate makes dihe...

The formulations contained different acrylate monomer with different structure and functionalities and TiO2, were applied to obtain pigmented acrylic films by UV exposure. The conversion and mechanical characteristic were correlated. The results showed that there is a significant interaction between pigment, reactive diluents’ type and mechanical properties of coatings. It seems that cured film...