BACKGROUND Up to 70% of patients with non-muscle-invasive bladder cancer (NMIBC) experience disease recurrence, making it one of the most prevalent cancers in the United States. The purpose of this study was to test the performance of a multiplex urinary biomarker assay for the monitoring of voided urine for recurrent bladder cancer. METHODS This retrospective, multicenter study included a to...

BACKGROUND Urinary Bladder cancer is a life threatening and aggressive disease. This retrospective study was conducted in Baluchistan for assessing the risk factors for urinary bladder cancer. METHOD A questionnaire was developed in order to collect the requisite information about the characteristics like age, drinking habits, smoking history, family history of cancer and others factors. Inte...

PURPOSE The purpose of this study was to identify proteins that are potentially involved in the tumor invasion of bladder cancer. EXPERIMENTAL DESIGN We searched for the candidate proteins by comparing the profiles of secreted proteins among the poorly invasive human bladder carcinoma cell line RT112 and the highly invasive cell line T24. The proteins isolated from cell culture supernatants w...

The proportion of ail cancers represented by urinary bladder cancer varies greatly wi thin Africa and the Middle East, and the ratio of male to female frequency of occurrence is nearly as variable (Parkin, 1986). ln Egyt, the proportion of bladder cancers among aIl cancers in men is twce that in Zambia, four times that in Zimbabwe and 10 times that in Algeria. Very few formai assessments of the...

The diagnosis of bladder cancer is generally made by cystoscopy and biopsy. Moreover, bladder cancer has a very high frequency of recurrence and therefore requires follow-up cystoscopy, along with urine cytology, as periodic surveillance to identify recurrence early. Cystoscopy is invasive and apt with complications like urine infection which sometimes lead to septicaemia with serious consequen...

BACKGROUND Urinary bladder carcinoma is common urological malignancy. Although epidemiological evidence favors role of occupational exposure to chemical carcinogen as the aetiological factor of bladder carcinoma, many cases arise with no obvious occupational exposure to chemical carcinogen. Tobacco and cigarette smoking is common in both rural and urban areas of Nepal. OBJECTIVE The objective...

Objective To evaluate the contemporary prevalence of urinary tract cancer (bladder cancer, upper urothelial [UTUC] and renal cancer) in patients referred to secondary care with haematuria, adjusted for established patient risk markers geographical variation. Patients Methods This was an international multicentre prospective observational study. We included aged ?16 years, suspected cancer. a kn...

Cystoscopy has remained the gold standard for the detection of bladder cancer for decades. Although many new fancy molecular markers have been developed and are widely applied in the diagnosis and management of various cancers today, no single marker has dethroned cystoscopy as " the tool " in the detection of bladder cancer. Although advances in technology have provided fluorescence and narrow...

A variable but often significant proportion of urinary bladder cancer in urban areas can be attributed to occupational and cultural (cigarette smoking) situations associated with exposures to various arylamines. The variable N-acetylation of carcinogenic arylamines by human hepatic enzyme systems, the known genetic regulation and polymorphic distribution of this enzyme activity in humans, and t...