Science-Metrix specializes in the measurement and evaluation of science, technology and innovation. Our data collection and assessment methods include bibliometrics, scientometrics, technometrics, surveys and interviews, environmental scans, monitoring and intelligence gathering. We perform program and policy evaluations, benchmarking and sector analyses, market studies and strategic planning. ...

Executive Summary This study aimed to evaluate the potential of pharmacogenomic science and technology (S&T) in Canada. In order to do so, the multiple scientific and ethical issues related to pharmacogenomic research were reviewed. Scientometric and technometric analyses were performed to provide a quantitative evaluation of Canada's performance in this field relative to that of the world and ...

BACKGROUND Sadat-Habdan Mesenchymal Stimulating Peptide (SHMSP) was discovered and patented with USPTO in 2008. Studies have shown that SHMSP works as an angiogenesis factor. This study was done to evaluate pharmacokinetics (PK) in rats and toxicology studies in goats and rats. METHODS In 80 skeletally mature Sprague Dawley rats 5 milligram/kg body weight of SHMSP was injected intramuscularly...

The groundswell of mergers and acquisitions in the plant biotechnology industry over the last decade has been driven by the research assets required to develop new biotechnology products and by the strong patent system of the United States. These mergers generate concern that the concentration of patents, plant germplasm, and markets for biotechnology among a few firms may be causing a decline ...

a r t i c l e i n f o We investigate how a deferred patent examination system promotes ex-ante screening of patent applications, which reduces both the number of granted patents and the use of economic resources for examinations, without reducing the return from R&D. Based on a real option theory, we develop a model of examination request behaviors. Exploiting the responses of Japanese firms to...

BACKGROUND In 2000, cervical acid phosphatase (CAP) has been recently described as a biomarker labeling abnormal squamous cells on Pap smears (USPTO #6,143,512). The enzyme activity is presented as a red, granular deposit on a modified Papanicolaou background. This unique property was utilized for development of MarkPap technology intended for cervical cancer screening. MATERIAL/PATIENTS & ME...

One of the most significant outcomes of genomics has been a rapid increase in the rate that we as a community can generate data on interesting biological systems. Rapid improvements in technologies such as DNA microarrays and proteomics applications have produced a climate where the challenge is no longer collecting high quality data but rather managing and analyzing it. As we in the bioinforma...

Research supported by this grant entitled “Passive Sensor Materials Based on Liquid Crystals” revolved around an investigation of liquid crystalline materials for use in passive sensors for chemical agents, including sulfur and phosphorus-containing compounds. The research was founded on the discovery in the Abbott research group at University of Wisconsin that competitive molecular interaction...