background: phenobarbital poisoning is common in vietnam. the aim of this study was to compare the effectiveness of continuous veno-venous hemofiltration (cvvh) and hemodialysis (hd) on clinical outcomes in the treatment of severe acute phenobarbital poisoning. methods: this was a retrospective observational historically controlled study. 42 patients with severe phenobarbital poisoning were enr...

INTRODUCTION Heparin-induced thrombocytopenia is an immune-mediated adverse drug reaction that is associated with a procoagulant state and both arterial and venous thrombosis. After observing two cases of repeated hemofiltration-filter clotting associated with high anti-PF4/heparin antibody concentrations, we systematically measured the anti-PF4/heparin antibody concentration in all cases of un...

Introduction Continuous veno-venous hemofiltration (CVVH) is often not continuous. Indeed, premature unplanned interruptions of sessions (UI) appear frequently. Nurses are directly implicated in the management of CVVH generators. High fidelity simulation (Sim) is an efficient method for health care provider training, mainly to improve procedural and knowledge skills. Taking advantage of the int...

Introduction Metformin is frequently used by type II diabetics. A rare complication of its use is metformin associated lactic acidosis (MALA). This condition is often accompanied by extreme metabolic acidosis and hemodynamic instability for which ICU treatment is mandatory. Guidelines advice intermittent hemodialysis for correction of metabolic acidosis and to clear metformin. However, haemodyn...

Even in patients with chronic renal failure and chronic intermittent hemodialysis, continuous venovenous hemofiltration (CVVH) is the most often practiced renal replacement technique in the intensive care unit. Although patients show less hemodynamic instability during CVVH than during hemodialysis, it requires a blood flow exceeding 200 ml/min in the extracorporeal circuit necessitating the us...

Acute renal failure is associated with increased mortality in the Pediatric Intensive Care Unit. When anuric or oliguric renal failure occurs, the associated fluid overload may compromise respiratory function and has been shown to be associated with worse outcomes. Renal replacement therapy using continuous venous-venous hemofiltration (CVVH) allows for fluid, solute, and nitrogenous waste remo...

Background: Phenobarbital poisoning is common in Vietnam. The aim of this study was to compare the effectiveness of continuous veno-venous hemofiltration (CVVH) and hemodialysis (HD) on clinical outcomes in the treatment of severe acute phenobarbital poisoning. Methods: This was a retrospective observational historically controlled study. 42 patients with severe phenobarbital poisoning were enr...

BACKGROUND Levetiracetam is an antiepileptic drug frequently used in critically ill patients. Levetiracetam is primarily eliminated as a parent compound via glomerular filtration and requires dose adjustment in renal insufficiency, but the literature on patients receiving continuous veno-venous hemofiltration (CVVH) is scant. CASE REPORT We report the levetiracetam pharmacokinetic profile of a ...

BACKGROUND It is not yet clear whether hemofiltration can reduce blood cytokine levels sufficiently to benefit patients who suffer prolonged cardiac arrest (CA) treated with cardiopulmonary bypass (CPB). We sought to assess effects of high-volume and standard volume continuous veno-venous hemofiltration (CVVH) on blood cytokine levels and survival in a rat model of prolonged CA treated with CPB...

BACKGROUND Blood hemoperfusion with resin adsorption can clean larger molecules that exceed the molecular weight cutoff of combined continuous veno-venous hemofiltration (CVVH). Hence blood hemoperfusion with resin adsorption combined CVVH (HP+CVVH) has higher ability of mediator clearance, and can improve clinical outcomes in theory. This study aimed to investigate the effect of blood hemoperf...