It is thought that the contents of water-soluble vitamins in the body are generally low in diabetic patients because large amounts of vitamins are excreted into urine. However, this hypothesis has not been confirmed. To investigate this hypothesis, diabetes was induced in male Wistar rats (6 wk old) by streptozotocin treatment, and they were then given diets containing low, medium or sufficient...

background bronchopulmonary dysplasia (bpd) is one of the most common serious squeal of preterm infants. it involves approximately one quarter of infants with birth weight less than 1500 grams and 30% of less than 1000 grams. vitamin a has been shown to reduce bpd rate. we compared efficacy of low and high doses of vitamin a for prevention of bpd in very low birth weight preterm infants. materi...

BACKGROUND Asymptomatic Indian lacto vegetarians, who make up more than half of the Indian population in different geographic regions, have distinctly low vitamin B-12 concentrations than non- vegetarians. Vegetarians consume milk but it seems that the amount is not enough to improve vitamin B-12 status or vitamin B-12 concentration in milk itself may be low. The aim of this study was to determ...

Fig. 1. Time course for a patient with refractory Burkitt’s leukemia who suffered from fungemia due to Trichosporon dermatis after chemotherapy. Abbreviations: R-hyper CVAD, rituximab+cyclophosphamide hydrate+vincristine sulfate+doxorubicin hydrochloride+dexamethasone; MTX, methotrexate; R-IVAC, rituximab+ifosfamide+etoposide+cytarabine; R-CODOX-M, rituximab+cyclophosphamide hydrate+vincristine...

BACKGROUND The concentration of total homocysteine (tHcy) is higher in newborns than in older children. Vitamin B-12 is the major determinant of tHcy in newborns. Maternal status of folate, vitamin B-12, and vitamin B-6 during pregnancy may affect the biochemical markers of these micronutrients in newborns. OBJECTIVE Our objective was to study the relation between concentrations of the metabo...

In vitamin B-12 (cobalamin) deficiency the metabolism of propionyl-CoA and methylmalonyl-CoA are inhibited secondarily to decreased L-methylmalonyl-CoA mutase activity. Production of acylcarnitines provides a mechanism for removing acyl groups and liberating CoA under conditions of impaired acyl-CoA utilization. Carnitine metabolism was studied in the vitamin B-12-deficient rat to define the re...

BACKGROUND Vitamin B(6) has attracted renewed interest because of its role in homocysteine metabolism and its possible relation to cardiovascular risk. We examined the plasma B(6) vitamers, pyridoxal 5'-phosphate (PLP), pyridoxal (PL), pyridoxine (PN), and 4-pyridoxic acid (4-PA) before and after vitamin B(6) supplementation. METHODS Patients (n = 90; age range, 38-80 years) undergoing corona...

BACKGROUND AND OBJECTIVES In Crohn's disease (CD), belonging to inflammatory bowel disease, the small intestine is involved in most cases. Most frequently affected is the distal ileum, where vitamin B-12 is specifically absorbed. Therefore, malabsorption of vitamin B-12 is quite likely to occur in patients with CD. In this study, we have studied the vitamin B-12 status in CD patients. METHODS...

Ascorbic acid (vitamin C) is involved in many vital biochemical processes the human body. Rose hips are a natural source of ascorbic acid. used decoctions and vitamin herbal teas. Russian compendial methods for quantitative determination have certain limitations precluding its objective measurement drugs, drug preparations, medicinal products. The aim study was to develop an analytical procedur...

Background: Vitamin B 6 is thought to be a most versatile coenzyme that participates in more than 100 biochemical reactions. It is involved in amino acid and homocysteine metabolism, glucose and lipid metabolism, neurotransmitter production and DNA/RNA synthesis. Vitamin B 6 can also be a modulator of gene expression. Nowadays, clinically evident vitamin B 6 deficiency is not a common disorder,...