Previous studies have reported that high concentrations of homocysteine and lower concentrations of vitamins B6, B12, and folate increase the risk for cognitive decline and pathology in aging populations. In this cross-sectional study, high resolution magnetic resonance imaging (MRI) scans and a 3-day food diary were collected on 32 community-dwelling adults between the ages of 59 and 79. We ex...

Plasma samples from suckling beef calves, transport-stressed weaned calves, 500 kg feedlot cattle, and lactating dairy cows were analyzed for vitamin C, folic acid, pantothenic acid, and vitamin B12' Plasma from stressed calves also was analyzed for vitamin B6' Differences in plasma levels were detected between groups. Plasma vitamin C was highest in suckling calves, but similar for stressed ca...

Patients with rheumatoid arthritis show several metabolic abnormalities, including abnormal tryptophan metabolism (Bett, 1962a, b; Flinn, Price, Yess, and Brown, 1964). This was postulated as due to a functional deficiency in vitamin B6 (Flinn and others, 1964), and McKusick, Sherwin, Jones, and Hsu (1964) did in fact demonstrate low urinary B6 in patients with rheumatoid arthritis. An alternat...

Vitamin B6 is a water-soluble vitamin, and is readily metabolized and excreted, so it has generally been assumed to have negligible toxicity, although at very high levels of intake it can cause peripheral nerve damage. Nutritional deficiency disease is extremely rare, although a significant proportion of the population shows biochemical evidence of inadequate status, despite apparently adequate...

BACKGROUND Since premenstrual syndrome (PMS) can cause suicide, dissociation of familial relationships, abnormalities in the daily work and inter-personal relationships in the patients, and bring about direct and indirect economic burden for the society, it is important to resolve the problems of the patients. The objective of the current study is to determine the effect of magnesium (Mg), comb...

PURPOSE Carpal tunnel syndrome (CTS) refers to a cluster of signs and symptoms that stems from compression of the median nerve traveling through carpal tunnel. Surgery is a definite treatment for CTS; however, many conservative therapies have been proposed. The present study set out to assess the effect of vitamin B6 in patients with CTS. METHODS Forty patients (67 hands) with mild-moderate C...

Patients infected with Schistosoma mansoni showed an abnormal response to a test dose of tryptophan, with little increase in the urinary excretion of kynurenine, hydroxykynurenine, xanthurenic and kynurenic acids, N1-methyl nicotinamide, methyl pyridone carboxamide, 5-hydroxytryptamine or 5-hydroxyindoleacetic acid. In contrast to previous reports, this is different from the pattern of tryptoph...