نتایج جستجو برای: vitiligo

تعداد نتایج: 3441  

2011
Katelyn T. Byrne Mary Jo Turk

Melanoma-associated vitiligo is the best-studied example of the linkage between tumor immunity and autoimmunity. Although vitiligo is an independent positive prognostic factor for melanoma patients, the autoimmune destruction of melanocytes was long thought to be merely a side effect of robust anti-tumor immunity. However, new data reveal a key role for vitiligo in supporting T cell responses t...

2009
Alicia Cecile Borderé Jo Lambert Nanny van Geel

Correspondence: Nanny van Geel Department of Dermatology, De Pintelaan 185, 9000 Ghent, Belgium Tel +32 9 332 22 87 Fax +32 9 332 49 96 Email [email protected] Abstract: Vitiligo is an acquired cutaneous disorder of pigmentation, with an incidence of 0.5% to 2% worldwide. There are three major hypotheses for the pathogenesis of vitiligo that are not exclusive of each other: biochemical/cyt...

2017
Huma Khurrum Khalid M. AlGhamdi Khalid M. Bedaiwi Naif Meshael AlBalahi

BACKGROUND The Koebner phenomenon (KP) is a common entity observed in dermatological disorders. The reported incidence of KP in vitiligo varies widely. Although the KP is frequently observed in patients with viltiligo, the associated factors with KP has not been established yet. OBJECTIVE The aim is to estimate the prevalence of KP in vitiligo patients and to investigate the associated factor...

Journal: :JAMA dermatology 2016
Camille Hua Lise Boussemart Christine Mateus Emilie Routier Céline Boutros Hugo Cazenave Roxane Viollet Marina Thomas Séverine Roy Naima Benannoune Gorana Tomasic Jean-Charles Soria Stéphane Champiat Matthieu Texier Emilie Lanoy Caroline Robert

IMPORTANCE Vitiligo is an autoimmune skin disorder that reacts against melanocytes. The association of vitiligo with tumor response in patients with melanoma who undergo immunotherapy has been reported but is still controversial. OBJECTIVE To prospectively evaluate the appearance of vitiligo in patients receiving pembrolizumab, a monoclonal antibody directed against the programmed death cell ...

2017
Shahnawaz D Jadeja Mohmmad Shoab Mansuri Mala Singh Mitesh Dwivedi Naresh C Laddha Rasheedunnisa Begum

BACKGROUND Autoimmunity has been implicated in the destruction of melanocytes from vitiligo skin. Major histocompatibility complex (MHC) class-II linked genes proteasome subunit beta 8 (PSMB8) and transporter associated with antigen processing 1 (TAP1), involved in antigen processing and presentation have been reported to be associated with several autoimmune diseases including vitiligo. OBJE...

2012
Esra Guney Gulunay Akcali Betul Ilkay Akcay Cihan Unlu Gurkan Erdogan Tahir Kansu Bozkurt Huseyin Bayramlar

Behçet's disease (BD) and vitiligo are diseases of unknown etiology. Interferon (IFN) alpha therapy is commonly used in Behçet uveitis. Interferon treatment in various diseases have also been observed causing certain autoimmune diseases such as vitiligo because of its immunomodulatory activity. The association between IFN therapy and vitiligo has been reported in the literature. We report a 21-...

Journal: :The British journal of dermatology 2015
K Ezzedine P E Grimes J-M Meurant J Seneschal C Léauté-Labrèze F Ballanger T Jouary C Taïeb A Taïeb

DEAR EDITOR, Vitiligo, an acquired, idiopathic skin disease characterized by a generally progressive loss of inherited skin colour, has an estimated worldwide prevalence of 0 5–1%. Although vitiligo is more noticeable in individuals with dark skin, the prevalence is similar to that in the overall population. Despite not being life threatening, vitiligo is a serious skin disorder and the overall...

2012
Mohammad Ali Nilforoushzadeh Gelavizh Keshtmand Fariba Jaffary Abbas Kheirkhah

Diphencyprone (DCP) is a contact sensitizer which is used to treat dermatological disorders with an immunological origin, such as extensive alopecia areata (AA). Vitiligo is a rare but known side effect of DPCP therapy which is formed in the treatment site or remote areas. In this paper a 37-year-old man developed alopecia totalis with loss of eyebrows and eyelashes who presented some vitiligo ...

2014
Sharmila Patil Manjyot Gautam Nitin Nadkarni Neha Saboo Kiran Godse Maninder Singh Setia

Background. Vitiligo has important clinical and social consequences particularly in the pigmented skin. The present study was conducted to assess the differences in clinicoepidemiological presentation of vitiligo in males and females and to understand the factors associated with spread of vitiligo in them. Methods. This is a cross-sectional analysis of secondary clinical data of 168 vitiligo pa...

2017
Fariba Iraji Seyed Hossin Banihashemi Gita Faghihi Zabihollah Shahmoradi Nabet Tajmirriahi Safoura Bokaie Jazi

BACKGROUND Vitiligo, a common disorder of depigmentation, is often difficult to treat. Corticosteroids are known to be effective, but with modest results. Although simvastatin has been reported to be effective for immunorelated dermatologic disorders including vitiligo, controlled trials are lacking. This study was conducted to compare the efficacy of topical betamethasone valerate 0.1% cream (...

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