نتایج جستجو برای: vitiligo

تعداد نتایج: 3441  

Journal: :The Journal of dermatology 2011
Reza Yaghoobi Mohammad Omidian Nooshin Bagherani

Vitiligo is a common depigmenting skin disorder, characterized by acquired, idiopathic, progressive, circumscribed hypomelanosis of the skin and hair, with total absence of melanocytes microscopically. It occurs worldwide, with an incidence rate of between 0.1% and 2%. Vitiligo is an important skin disease having a major impact on the quality of life of the patient suffering from it. The causes...

2016
Christian Diehl

Obviously, vitiligo is a multifactorial disease, and at this stage, we all accept that the autoimmune theory, the adhesion defect theory and the biochemical theory based on oxidative stress are the mainstays of our current knowledge about the aetiology of the disease. The presence of an imbalance in the anti-oxidant system in vitiligo melanocytes was assessed early, providing support for a free...

2015
Natasha Ferraroni Rosemeire Navickas Constantino-Silva Camila Cacere Juliano Cesar Barros Rafael Aragon Cabrera Anete Grumach Carlos D'apparecida Santos Machado Filho

Background Vitiligo is a skin disorder that affects 1% to 2% of the world population, independently of ethnicity. It presents with white plaques and skin discoloration. The presence of antibodies against melanocytes confirms the autoimmune phenomena in this disease. Regarding cellular imune response in active vitiligo, it seems to be an imbalance between T cell CD8+ and CD4+, and, moreover, an ...

Journal: :Acta dermato-venereologica 2011
Ayse Serap Karadag Emre Tutal Derun Taner Ertugrul

The aim of this study was to evaluate the relationship between vitiligo and insulin resistance (IR). A total of 96 subjects were included in the study; 57 patients with vitiligo and 39 subjects in an age and a body mass index-matched control group. In fasting blood samples, insulin, C-peptide, glucose, total cholesterol, triglyceride, low-density lipoprotein-cholesterol (LDL-C) and high-density...

Journal: :Indian journal of dermatology, venereology and leprology 2008
Dilip Kachhawa Gyaneshwar Kalla

BACKGROUND Various surgical procedures for correcting stable vitiligo exist but these have their own limitations. Autologous, non-cultured, non-trypsinized, melanocyte plus keratinocyte grafting is a new and simple method of vitiligo surgery. OBJECTIVE The study aimed to evaluate efficacy of a new grafting technique in vitiligo patches. METHODS Eighteen vitiligo patches underwent this proce...

Journal: :JAMA ophthalmology 2013
Pukhraj Rishi Carol L Shields Kaitlin Patrick Jerry A Shields

IMPORTANCE The relationship of vitiligo to cutaneous melanoma is believed to be due to an immune response generated to melanoma antigens that cross-react with normal skin. There is little in the literature on the relationship between cutaneous vitiligo and uveal melanoma. OBJECTIVE To describe the clinical profile, treatment, and outcome in patients with uveal melanoma who subsequently develo...

Journal: :International journal of dermatology 2014
Zeinab A Ibrahim Nahla R Ghaly Rania A El-Tatawy Shereen M Khalil Manal M El-Batch

BACKGROUND A proliferation-inducing ligand (APRIL) is a tumor necrosis factor (TNF) superfamily member ligand that stimulates B cells in vitro and in vivo. It also plays an important role in T cell activation and survival. OBJECTIVES This study was conducted to evaluate serum levels of APRIL in patients with atopic dermatitis (AD) and vitiligo and their correlation with disease activity. ME...

2016
Kosar Hedayat Mojgan Karbakhsh Maryam Ghiasi Azadeh Goodarzi Yousef Fakour Zahra Akbari Afsaneh Ghayoumi Narges Ghandi

BACKGROUND Vitiligo is a multi-factorial pigmentary skin disorder. Recently, the importance of emotional and psychological issues is proposed in incidence, progression, relapse and remission of vitiligo. There are limited studies conducted in developing countries, which assess life quality of patients with vitiligo. The aim of this study was the application and evaluation of a disease-specific ...

Journal: :iranian journal of psychiatry 0
masoomeh saeedloo mental health research center and faculty of medicine, iran university of medical sciences, tehran, iran seyed vahid shariat mental health research center and department of psychiatry, tehran institute of psychiatry-faculty of behavioral sciences and mental health, iran university of medical sciences, tehran, iran

objective: vitiligo is a rare side effect of carbamazepine whose exact mechanism is unknown. the aim of this report is to describe a single case of vitiligo induced by carbamazepine . methods: the case was a patient with bipolar i disorder whose medications were changed from valproate to carbamazepine and who developed vitiligo after a short while. we followed the case for about four years when...

2012
Shyam Bhanushankar Verma Uwe Wollina

Vitiligo is a dreaded disease in India due to its social and cultural consequences. PUVA and PUVAsol are the main treatment modalities for vitiligo vulgaris. To the best of our knowledge, this is the first case of accidental PUVA burns eventuating in prurigo nodularis lesions to be reported in a female patient who was undergoing home PUVA therapy. The itch is so prominent and disabling that the...

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