Objective: To examine the effect of warm and cold ischemia on functions of the operated kidney in cases with a normal contralateral kidney undergoing nephron sparing surgery. Methods: This study enrolled 40 patients with a normal contralateral kidney and without a renal function threatening risk factor, who were operated with NSS. The patients were randomized at admission. They were divided int...

INTRODUCTION AND OBJECTIVES Laparoscopic partial nephrectomy (LPN) is a challenging procedure that requires quick and effective intracorporeal suturing, that could limit widespread adoption. Refinements of surgery have improved warm ischemia times and facilitated renal reconstruction. We present a technique that makes renorrhaphy easier using Self-Retaining Barbed Suture (SRBS) weaving two thre...

OBJECTIVE To develop a combined surgical approach (laparoscopic and open) that allows an increased vascular control and decreased ischemia time, maintaining the advantages of pure laparoscopic partial nephrectomy (LPN). MATERIAL AND METHODS During the laparoscopic phase, dissection of the kidney and its pedicle is achieved. Then, an open approach is initiated through a mini-laparotomy, with t...

COMPLEMENT is gradually being considered in ischemia-reperfusion, especially in xenotransplantation. Reperfusion injury is characterized by deposition of C3 and C5b-9. Complement inhibitors are used in amelioration of warm ischemia and rejection episodes. Tranexamic acid (Amca), a synthetic antifibrinolytic agent, has proven to be effective in acquired angioedema (a deficiency of the C1 inhibit...

INTRODUCTION The objective is to determine the clinical and experimental evidences of the renal responses to warm and cold ischemia, kidney tolerability, and available practical techniques of protecting the kidney during nephron-sparing surgery. MATERIALS AND METHODS Review of the English and non-English literature using MEDLINE, MD Consult, and urology textbooks. RESULTS AND DISCUSSION The...

PURPOSE The learning curve for robot-assisted partial nephrectomy (RAPN) has not been extensively studied. We therefore evaluated the learning curve of RAPN for a fellowship-trained laparoscopic surgeon with extensive prior experience with laparoscopic partial nephrectomy (LPN). We also examined the potential effect of tumor size on the learning curve. PATIENTS AND METHODS We prospectively ev...