Transducer of Cdc42-dependent actin assembly (Toca-1) consists of an F-BAR domain, a Cdc42 binding site and an SH3 domain. Toca-1 interacts with N-WASP, an activator of actin nucleation that binds Cdc42. Cdc42 may play an important role in regulating Toca-1 and N-WASP functions. We report here that the cellular expression of Toca-1 and N-WASP induces membrane tubulation and the formation of mot...

The accurate simulation of SWAT can assist the government in making correct decisions about water management practices, which are important for human health, agricultural management, industry development, environmental quality, flood risk assessment, and recreation. In this project, the PIs were trying to improve the simulation accuracy of the SWAT model through developing new algorithm to obta...

Precise regulation of synapses during development is essential to ensure accurate neural connectivity and function of nervous system. Many signaling pathways, including the mTOR (mechanical Target of Rapamycin) pathway operate in neurons to maintain genetically determined number of synapses during development. mTOR, a kinase, is shared between two functionally distinct multi-protein complexes- ...

This paper describes the Time series analysis of river water quality with emphasis on variation in parameters as evidenced by statistical approach and mathematical models. The extensive study enabled to differentiate and realize the behaviour of river and catchment's changes induced by human activities. The Time series analysis evaluation indicated trivial variation and movement in the water qu...

Predicting the levels of chlorophyll-a (Chl-a) is a vital component of water quality management, which ensures that urban drinking water is safe from harmful algal blooms. This study developed a model to predict Chl-a levels in the Yuqiao Reservoir (Tianjin, China) biweekly using water quality and meteorological data from 1999-2012. First, six artificial neural networks (ANNs) and two non-ANN m...

design, simulation and optimal selection of cosine-linear frequency modulation waveform (cnlfm) based on correlated ambiguity function (af) method for the purpose of synthetic aperture radar (sar) is done in this article. the selected optimum cnlfm waveform in contribution with other waveforms are applied directly into a sar image formation algorithm (ifa) and their quality effects performance ...